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Strain-induced mechanotransduction through primary cilia, extracellular ATP, purinergic calcium signaling, and ERK1/2 transactivates CITED2 and downregulates MMP-1 and MMP-13 gene expression in chondrocytes.
He Z, Leong DJ, Zhuo Z, Majeska RJ, Cardoso L, Spray DC, Goldring MB, Cobelli NJ, Sun HB. He Z, et al. Among authors: leong dj. Osteoarthritis Cartilage. 2016 May;24(5):892-901. doi: 10.1016/j.joca.2015.11.015. Epub 2015 Dec 12. Osteoarthritis Cartilage. 2016. PMID: 26687824 Free article.
Events in articular chondrocytes with aging.
Leong DJ, Sun HB. Leong DJ, et al. Curr Osteoporos Rep. 2011 Dec;9(4):196-201. doi: 10.1007/s11914-011-0070-3. Curr Osteoporos Rep. 2011. PMID: 21912847 Review.
Mechanotransduction and cartilage integrity.
Leong DJ, Hardin JA, Cobelli NJ, Sun HB. Leong DJ, et al. Ann N Y Acad Sci. 2011 Dec;1240:32-7. doi: 10.1111/j.1749-6632.2011.06301.x. Ann N Y Acad Sci. 2011. PMID: 22172037 Free PMC article. Review.
51 results