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RIP140 deficiency enhances cardiac fuel metabolism and protects mice from heart failure.
Yamamoto T, Maurya SK, Pruzinsky E, Batmanov K, Xiao Y, Sulon SM, Sakamoto T, Wang Y, Lai L, McDaid KS, Shewale SV, Leone TC, Koves TR, Muoio DM, Dierickx P, Lazar MA, Lewandowski ED, Kelly DP. Yamamoto T, et al. Among authors: leone tc. J Clin Invest. 2023 May 1;133(9):e162309. doi: 10.1172/JCI162309. J Clin Invest. 2023. PMID: 36927960 Free PMC article.
Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism.
Gan Z, Rumsey J, Hazen BC, Lai L, Leone TC, Vega RB, Xie H, Conley KE, Auwerx J, Smith SR, Olson EN, Kralli A, Kelly DP. Gan Z, et al. Among authors: leone tc. J Clin Invest. 2013 Jun;123(6):2564-75. doi: 10.1172/JCI67652. Epub 2013 May 8. J Clin Invest. 2013. PMID: 23676496 Free PMC article.
The Failing Heart Relies on Ketone Bodies as a Fuel.
Aubert G, Martin OJ, Horton JL, Lai L, Vega RB, Leone TC, Koves T, Gardell SJ, Krüger M, Hoppel CL, Lewandowski ED, Crawford PA, Muoio DM, Kelly DP. Aubert G, et al. Among authors: leone tc. Circulation. 2016 Feb 23;133(8):698-705. doi: 10.1161/CIRCULATIONAHA.115.017355. Epub 2016 Jan 27. Circulation. 2016. PMID: 26819376 Free PMC article.
Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure.
Yurista SR, Matsuura TR, Silljé HHW, Nijholt KT, McDaid KS, Shewale SV, Leone TC, Newman JC, Verdin E, van Veldhuisen DJ, de Boer RA, Kelly DP, Westenbrink BD. Yurista SR, et al. Among authors: leone tc. Circ Heart Fail. 2021 Jan;14(1):e007684. doi: 10.1161/CIRCHEARTFAILURE.120.007684. Epub 2020 Dec 28. Circ Heart Fail. 2021. PMID: 33356362 Free PMC article.
Mitochondrial protein hyperacetylation in the failing heart.
Horton JL, Martin OJ, Lai L, Riley NM, Richards AL, Vega RB, Leone TC, Pagliarini DJ, Muoio DM, Bedi KC Jr, Margulies KB, Coon JJ, Kelly DP. Horton JL, et al. Among authors: leone tc. JCI Insight. 2016 Feb;2(1):e84897. doi: 10.1172/jci.insight.84897. Epub 2016 Feb 25. JCI Insight. 2016. PMID: 26998524 Free PMC article.
Fueling Cardiac Hypertrophy.
Matsuura TR, Leone TC, Kelly DP. Matsuura TR, et al. Among authors: leone tc. Circ Res. 2020 Jan 17;126(2):197-199. doi: 10.1161/CIRCRESAHA.119.316358. Epub 2020 Jan 16. Circ Res. 2020. PMID: 31944916 Free PMC article. No abstract available.
47 results