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Human cortical interneurons optimized for grafting specifically integrate, abort seizures, and display prolonged efficacy without over-inhibition.
Zhu Q, Mishra A, Park JS, Liu D, Le DT, Gonzalez SZ, Anderson-Crannage M, Park JM, Park GH, Tarbay L, Daneshvar K, Brandenburg M, Signoretti C, Zinski A, Gardner EJ, Zheng KL, Abani CP, Hu C, Beaudreault CP, Zhang XL, Stanton PK, Cho JH, Velíšek L, Velíšková J, Javed S, Leonard CS, Kim HY, Chung S. Zhu Q, et al. Among authors: leonard cs. Neuron. 2023 Mar 15;111(6):807-823.e7. doi: 10.1016/j.neuron.2022.12.014. Epub 2023 Jan 9. Neuron. 2023. PMID: 36626901 Free PMC article.
Orexin Receptor Activation Generates Gamma Band Input to Cholinergic and Serotonergic Arousal System Neurons and Drives an Intrinsic Ca(2+)-Dependent Resonance in LDT and PPT Cholinergic Neurons.
Ishibashi M, Gumenchuk I, Kang B, Steger C, Lynn E, Molina NE, Eisenberg LM, Leonard CS. Ishibashi M, et al. Among authors: leonard cs. Front Neurol. 2015 Jun 2;6:120. doi: 10.3389/fneur.2015.00120. eCollection 2015. Front Neurol. 2015. PMID: 26082752 Free PMC article.
Age-related changes in nicotine response of cholinergic and non-cholinergic laterodorsal tegmental neurons: implications for the heightened adolescent susceptibility to nicotine addiction.
Christensen MH, Ishibashi M, Nielsen ML, Leonard CS, Kohlmeier KA. Christensen MH, et al. Among authors: leonard cs. Neuropharmacology. 2014 Oct;85:263-83. doi: 10.1016/j.neuropharm.2014.05.010. Epub 2014 May 24. Neuropharmacology. 2014. PMID: 24863041 Free PMC article.
Differential actions of orexin receptors in brainstem cholinergic and monoaminergic neurons revealed by receptor knockouts: implications for orexinergic signaling in arousal and narcolepsy.
Kohlmeier KA, Tyler CJ, Kalogiannis M, Ishibashi M, Kristensen MP, Gumenchuk I, Chemelli RM, Kisanuki YY, Yanagisawa M, Leonard CS. Kohlmeier KA, et al. Among authors: leonard cs. Front Neurosci. 2013 Dec 20;7:246. doi: 10.3389/fnins.2013.00246. eCollection 2013. Front Neurosci. 2013. PMID: 24391530 Free PMC article.
Orexin/hypocretin receptor signalling cascades.
Kukkonen JP, Leonard CS. Kukkonen JP, et al. Among authors: leonard cs. Br J Pharmacol. 2014 Jan;171(2):314-31. doi: 10.1111/bph.12324. Br J Pharmacol. 2014. PMID: 23902572 Free PMC article. Review.
51 results