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Beta-glucan contamination of pharmaceutical products: How much should we accept?
Cancer Immunol Immunother. 2016 Nov;65(11):1289-1301. doi: 10.1007/s00262-016-1875-9. Epub 2016 Jul 29.
Cancer Immunol Immunother. 2016.
PMID: 27473075
Free PMC article.
Review.
Development of downstream processing to minimize beta-glucan impurities in GMP-manufactured therapeutic antibodies.
Vigor K, Emerson J, Scott R, Cheek J, Barton C, Bax HJ, Josephs DH, Karagiannis SN, Spicer JF, Lentfer H.
Vigor K, et al. Among authors: lentfer h.
Biotechnol Prog. 2016 Nov;32(6):1494-1502. doi: 10.1002/btpr.2359. Epub 2016 Oct 21.
Biotechnol Prog. 2016.
PMID: 27604040
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Potential for monocyte recruitment by IgE immunotherapy for cancer in a rat model of tumour metastasis.
Josephs DH, Bax HJ, Lentfer H, Selkirk C, Spicer JF, Karagiannis SN.
Josephs DH, et al. Among authors: lentfer h.
Lancet. 2015 Feb 26;385 Suppl 1:S53. doi: 10.1016/S0140-6736(15)60368-3.
Lancet. 2015.
PMID: 26312875
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Anti-Folate Receptor-α IgE but not IgG Recruits Macrophages to Attack Tumors via TNFα/MCP-1 Signaling.
Josephs DH, Bax HJ, Dodev T, Georgouli M, Nakamura M, Pellizzari G, Saul L, Karagiannis P, Cheung A, Herraiz C, Ilieva KM, Correa I, Fittall M, Crescioli S, Gazinska P, Woodman N, Mele S, Chiaruttini G, Gilbert AE, Koers A, Bracher M, Selkirk C, Lentfer H, Barton C, Lever E, Muirhead G, Tsoka S, Canevari S, Figini M, Montes A, Downes N, Dombrowicz D, Corrigan CJ, Beavil AJ, Nestle FO, Jones PS, Gould HJ, Sanz-Moreno V, Blower PJ, Spicer JF, Karagiannis SN.
Josephs DH, et al. Among authors: lentfer h.
Cancer Res. 2017 Mar 1;77(5):1127-1141. doi: 10.1158/0008-5472.CAN-16-1829. Epub 2017 Jan 17.
Cancer Res. 2017.
PMID: 28096174
Free PMC article.
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An immunologically relevant rodent model demonstrates safety of therapy using a tumour-specific IgE.
Josephs DH, Nakamura M, Bax HJ, Dodev TS, Muirhead G, Saul L, Karagiannis P, Ilieva KM, Crescioli S, Gazinska P, Woodman N, Lombardelli C, Kareemaghay S, Selkirk C, Lentfer H, Barton C, Canevari S, Figini M, Downes N, Dombrowicz D, Corrigan CJ, Nestle FO, Jones PS, Gould HJ, Blower PJ, Tsoka S, Spicer JF, Karagiannis SN.
Josephs DH, et al. Among authors: lentfer h.
Allergy. 2018 Dec;73(12):2328-2341. doi: 10.1111/all.13455. Epub 2018 Oct 8.
Allergy. 2018.
PMID: 29654623
Free PMC article.
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