Lenstra DC - Search Results

1

Investigating the active site of human trimethyllysine hydroxylase.

Wang Y, Reddy YV, Al Temimi AHK, Venselaar H, Nelissen FHT, Lenstra DC, Mecinović J. Wang Y, et al. Among authors: lenstra dc. Biochem J. 2019 Apr 10;476(7):1109-1119. doi: 10.1042/BCJ20180857. Biochem J. 2019. PMID: 30898847

2

Triphenylphosphine-catalysed amide bond formation between carboxylic acids and amines.

Lenstra DC, Rutjes FP, Mecinović J. Lenstra DC, et al. Chem Commun (Camb). 2014 Jun 1;50(43):5763-6. doi: 10.1039/c4cc01861c. Epub 2014 Apr 22. Chem Commun (Camb). 2014. PMID: 24752820

3

Poly(methylhydrosiloxane) as a green reducing agent in organophosphorus-catalysed amide bond formation.

Hamstra DFJ, Lenstra DC, Koenders TJ, Rutjes FPJT, Mecinović J. Hamstra DFJ, et al. Among authors: lenstra dc. Org Biomol Chem. 2017 Aug 2;15(30):6426-6432. doi: 10.1039/c7ob01510k. Org Biomol Chem. 2017. PMID: 28737181

4

Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II).

Lenstra DC, Al Temimi AHK, Mecinović J. Lenstra DC, et al. Bioorg Med Chem Lett. 2018 Apr 15;28(7):1234-1238. doi: 10.1016/j.bmcl.2018.02.043. Epub 2018 Feb 24. Bioorg Med Chem Lett. 2018. PMID: 29519735 Free article.

5

Structure-Activity Relationship Studies on (R)-PFI-2 Analogues as Inhibitors of Histone Lysine Methyltransferase SETD7.

Lenstra DC, Damen E, Leenders RGG, Blaauw RH, Rutjes FPJT, Wegert A, Mecinović J. Lenstra DC, et al. ChemMedChem. 2018 Jul 18;13(14):1405-1413. doi: 10.1002/cmdc.201800242. Epub 2018 Jun 25. ChemMedChem. 2018. PMID: 29869845

6

Catalytic Staudinger Reduction at Room Temperature.

Lenstra DC, Wolf JJ, Mecinović J. Lenstra DC, et al. J Org Chem. 2019 May 17;84(10):6536-6545. doi: 10.1021/acs.joc.9b00831. Epub 2019 May 9. J Org Chem. 2019. PMID: 31050295

7

Importance of the main chain of lysine for histone lysine methyltransferase catalysis.

Al Temimi AHK, Teeuwen RS, Tran V, Altunc AJ, Lenstra DC, Ren W, Qian P, Guo H, Mecinović J. Al Temimi AHK, et al. Among authors: lenstra dc. Org Biomol Chem. 2019 Jun 12;17(23):5693-5697. doi: 10.1039/c9ob01038f. Org Biomol Chem. 2019. PMID: 31134245

8

Lysine Ethylation by Histone Lysine Methyltransferases.

Al Temimi AHK, Martin M, Meng Q, Lenstra DC, Qian P, Guo H, Weinhold E, Mecinović J. Al Temimi AHK, et al. Among authors: lenstra dc. Chembiochem. 2020 Feb 3;21(3):392-400. doi: 10.1002/cbic.201900359. Epub 2019 Oct 24. Chembiochem. 2020. PMID: 31287209 Free PMC article.

9

Novel SAR for quinazoline inhibitors of EHMT1 and EHMT2.

Leenders R, Zijlmans R, van Bree B, van de Sande M, Trivarelli F, Damen E, Wegert A, Müller D, Ehlert JE, Feger D, Heidemann-Dinger C, Kubbutat M, Schächtele C, Lenstra DC, Mecinović J, Müller G. Leenders R, et al. Among authors: lenstra dc. Bioorg Med Chem Lett. 2019 Sep 1;29(17):2516-2524. doi: 10.1016/j.bmcl.2019.06.012. Epub 2019 Jun 14. Bioorg Med Chem Lett. 2019. PMID: 31350126

10

Examining sterically demanding lysine analogs for histone lysine methyltransferase catalysis.

Temimi AHKA, Tran V, Teeuwen RS, Altunc AJ, Amatdjais-Groenen HIV, White PB, Lenstra DC, Proietti G, Wang Y, Wegert A, Blaauw RH, Qian P, Ren W, Guo H, Mecinović J. Temimi AHKA, et al. Among authors: lenstra dc. Sci Rep. 2020 Feb 28;10(1):3671. doi: 10.1038/s41598-020-60337-3. Sci Rep. 2020. PMID: 32111884 Free PMC article.

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