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ISG15 deficiency and increased viral resistance in humans but not mice.
Speer SD, Li Z, Buta S, Payelle-Brogard B, Qian L, Vigant F, Rubino E, Gardner TJ, Wedeking T, Hermann M, Duehr J, Sanal O, Tezcan I, Mansouri N, Tabarsi P, Mansouri D, Francois-Newton V, Daussy CF, Rodriguez MR, Lenschow DJ, Freiberg AN, Tortorella D, Piehler J, Lee B, García-Sastre A, Pellegrini S, Bogunovic D. Speer SD, et al. Among authors: lenschow dj. Nat Commun. 2016 May 19;7:11496. doi: 10.1038/ncomms11496. Nat Commun. 2016. PMID: 27193971 Free PMC article.
Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses.
Frias-Staheli N, Giannakopoulos NV, Kikkert M, Taylor SL, Bridgen A, Paragas J, Richt JA, Rowland RR, Schmaljohn CS, Lenschow DJ, Snijder EJ, García-Sastre A, Virgin HW 4th. Frias-Staheli N, et al. Among authors: lenschow dj. Cell Host Microbe. 2007 Dec 13;2(6):404-16. doi: 10.1016/j.chom.2007.09.014. Cell Host Microbe. 2007. PMID: 18078692 Free PMC article.
IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses.
Lenschow DJ, Lai C, Frias-Staheli N, Giannakopoulos NV, Lutz A, Wolff T, Osiak A, Levine B, Schmidt RE, García-Sastre A, Leib DA, Pekosz A, Knobeloch KP, Horak I, Virgin HW 4th. Lenschow DJ, et al. Proc Natl Acad Sci U S A. 2007 Jan 23;104(4):1371-6. doi: 10.1073/pnas.0607038104. Epub 2007 Jan 16. Proc Natl Acad Sci U S A. 2007. PMID: 17227866 Free PMC article.
ISG15 in antiviral immunity and beyond.
Perng YC, Lenschow DJ. Perng YC, et al. Among authors: lenschow dj. Nat Rev Microbiol. 2018 Jul;16(7):423-439. doi: 10.1038/s41579-018-0020-5. Nat Rev Microbiol. 2018. PMID: 29769653 Free PMC article. Review.
The antiviral activities of ISG15.
Morales DJ, Lenschow DJ. Morales DJ, et al. Among authors: lenschow dj. J Mol Biol. 2013 Dec 13;425(24):4995-5008. doi: 10.1016/j.jmb.2013.09.041. Epub 2013 Oct 3. J Mol Biol. 2013. PMID: 24095857 Free PMC article. Review.
Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.
Giannakopoulos NV, Luo JK, Papov V, Zou W, Lenschow DJ, Jacobs BS, Borden EC, Li J, Virgin HW, Zhang DE. Giannakopoulos NV, et al. Among authors: lenschow dj. Biochem Biophys Res Commun. 2005 Oct 21;336(2):496-506. doi: 10.1016/j.bbrc.2005.08.132. Biochem Biophys Res Commun. 2005. PMID: 16139798
67 results