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Real-time analysis of the cancer genome and fragmentome from plasma and urine cell-free DNA using nanopore sequencing.
van der Pol Y, Tantyo NA, Evander N, Hentschel AE, Wever BM, Ramaker J, Bootsma S, Fransen MF, Lenos KJ, Vermeulen L, Schneiders FL, Bahce I, Nieuwenhuijzen JA, Steenbergen RD, Pegtel DM, Moldovan N, Mouliere F. van der Pol Y, et al. Among authors: lenos kj. EMBO Mol Med. 2023 Dec 7;15(12):e17282. doi: 10.15252/emmm.202217282. Epub 2023 Nov 9. EMBO Mol Med. 2023. PMID: 37942753 Free PMC article.
The landscape of cell-free mitochondrial DNA in liquid biopsy for cancer detection.
van der Pol Y, Moldovan N, Ramaker J, Bootsma S, Lenos KJ, Vermeulen L, Sandhu S, Bahce I, Pegtel DM, Wong SQ, Dawson SJ, Chandrananda D, Mouliere F. van der Pol Y, et al. Among authors: lenos kj. Genome Biol. 2023 Oct 12;24(1):229. doi: 10.1186/s13059-023-03074-w. Genome Biol. 2023. PMID: 37828498 Free PMC article.
Cancer stem cells: here, there, and everywhere.
Lodestijn SC, Lenos KJ, Miedema DM, Bijlsma MF, Vermeulen L. Lodestijn SC, et al. Among authors: lenos kj. Mol Cell Oncol. 2018 Dec 4;6(1):1540235. doi: 10.1080/23723556.2018.1540235. eCollection 2019. Mol Cell Oncol. 2018. PMID: 30788417 Free PMC article.
Molecular characterization of colorectal cancer related peritoneal metastatic disease.
Lenos KJ, Bach S, Ferreira Moreno L, Ten Hoorn S, Sluiter NR, Bootsma S, Vieira Braga FA, Nijman LE, van den Bosch T, Miedema DM, van Dijk E, Ylstra B, Kulicke R, Davis FP, Stransky N, Smolen GA, Coebergh van den Braak RRJ, IJzermans JNM, Martens JWM, Hallam S, Beggs AD, Kops GJPL, Lansu N, Bastiaenen VP, Klaver CEL, Lecca MC, El Makrini K, Elbers CC, Dings MPG, van Noesel CJM, Kranenburg O, Medema JP, Koster J, Koens L, Punt CJA, Tanis PJ, de Hingh IH, Bijlsma MF, Tuynman JB, Vermeulen L. Lenos KJ, et al. Nat Commun. 2022 Aug 4;13(1):4443. doi: 10.1038/s41467-022-32198-z. Nat Commun. 2022. PMID: 35927254 Free PMC article.
Behavioral factors to modulate immunotherapy efficacy in cancer.
Jongerius C, Vermeulen L, van Egmond M, Evers AWM, Buffart LM, Lenos KJ. Jongerius C, et al. Among authors: lenos kj. Front Immunol. 2022 Dec 16;13:1066359. doi: 10.3389/fimmu.2022.1066359. eCollection 2022. Front Immunol. 2022. PMID: 36591246 Free PMC article.
Chromosomal copy number heterogeneity predicts survival rates across cancers.
van Dijk E, van den Bosch T, Lenos KJ, El Makrini K, Nijman LE, van Essen HFB, Lansu N, Boekhout M, Hageman JH, Fitzgerald RC, Punt CJA, Tuynman JB, Snippert HJG, Kops GJPL, Medema JP, Ylstra B, Vermeulen L, Miedema DM. van Dijk E, et al. Among authors: lenos kj. Nat Commun. 2021 May 27;12(1):3188. doi: 10.1038/s41467-021-23384-6. Nat Commun. 2021. PMID: 34045449 Free PMC article.
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