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Podocyte Injury in Diabetic Kidney Disease in Mouse Models Involves TRPC6-mediated Calpain Activation Impairing Autophagy.
Salemkour Y, Yildiz D, Dionet L, 't Hart DC, Verheijden KAT, Saito R, Mahtal N, Delbet JD, Letavernier E, Rabant M, Karras A, van der Vlag J, Nijenhuis T, Tharaux PL, Lenoir O. Salemkour Y, et al. Among authors: lenoir o. J Am Soc Nephrol. 2023 Nov 1;34(11):1823-1842. doi: 10.1681/ASN.0000000000000212. Epub 2023 Sep 6. J Am Soc Nephrol. 2023. PMID: 37678257
Direct action of endothelin-1 on podocytes promotes diabetic glomerulosclerosis.
Lenoir O, Milon M, Virsolvy A, Hénique C, Schmitt A, Massé JM, Kotelevtsev Y, Yanagisawa M, Webb DJ, Richard S, Tharaux PL. Lenoir O, et al. J Am Soc Nephrol. 2014 May;25(5):1050-62. doi: 10.1681/ASN.2013020195. Epub 2014 Apr 10. J Am Soc Nephrol. 2014. PMID: 24722437 Free PMC article.
Update on crescentic glomerulonephritis.
Hénique C, Papista C, Guyonnet L, Lenoir O, Tharaux PL. Hénique C, et al. Among authors: lenoir o. Semin Immunopathol. 2014 Jul;36(4):479-90. doi: 10.1007/s00281-014-0435-7. Epub 2014 Jun 20. Semin Immunopathol. 2014. PMID: 24948005 Review.
Nuclear Factor Erythroid 2-Related Factor 2 Drives Podocyte-Specific Expression of Peroxisome Proliferator-Activated Receptor γ Essential for Resistance to Crescentic GN.
Henique C, Bollee G, Lenoir O, Dhaun N, Camus M, Chipont A, Flosseau K, Mandet C, Yamamoto M, Karras A, Thervet E, Bruneval P, Nochy D, Mesnard L, Tharaux PL. Henique C, et al. Among authors: lenoir o. J Am Soc Nephrol. 2016 Jan;27(1):172-88. doi: 10.1681/ASN.2014111080. Epub 2015 May 21. J Am Soc Nephrol. 2016. PMID: 25999406 Free PMC article.
Endothelial Epas1 Deficiency Is Sufficient To Promote Parietal Epithelial Cell Activation and FSGS in Experimental Hypertension.
Luque Y, Lenoir O, Bonnin P, Hardy L, Chipont A, Placier S, Vandermeersch S, Xu-Dubois YC, Robin B, Lazareth H, Souyri M, Guyonnet L, Baudrie V, Camerer E, Rondeau E, Mesnard L, Tharaux PL. Luque Y, et al. Among authors: lenoir o. J Am Soc Nephrol. 2017 Dec;28(12):3563-3578. doi: 10.1681/ASN.2016090960. Epub 2017 Sep 19. J Am Soc Nephrol. 2017. PMID: 28928136 Free PMC article.
Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis.
Henique C, Bollée G, Loyer X, Grahammer F, Dhaun N, Camus M, Vernerey J, Guyonnet L, Gaillard F, Lazareth H, Meyer C, Bensaada I, Legrès L, Satoh T, Akira S, Bruneval P, Dimmeler S, Tedgui A, Karras A, Thervet E, Nochy D, Huber TB, Mesnard L, Lenoir O, Tharaux PL. Henique C, et al. Among authors: lenoir o. Nat Commun. 2017 Nov 28;8(1):1829. doi: 10.1038/s41467-017-01885-7. Nat Commun. 2017. PMID: 29184126 Free PMC article.
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