Lennernäs H - Search Results

1

In Vitro Cell Toxicity and Intracellular Uptake of Doxorubicin Exposed as a Solution or Liposomes: Implications for Treatment of Hepatocellular Carcinoma.

Kullenberg F, Degerstedt O, Calitz C, Pavlović N, Balgoma D, Gråsjö J, Sjögren E, Hedeland M, Heindryckx F, Lennernäs H. Kullenberg F, et al. Among authors: lennernas h. Cells. 2021 Jul 6;10(7):1717. doi: 10.3390/cells10071717. Cells. 2021. PMID: 34359887 Free PMC article.

2

Multiple transport mechanisms involved in the intestinal absorption and first-pass extraction of fexofenadine.

Tannergren C, Petri N, Knutson L, Hedeland M, Bondesson U, Lennernäs H. Tannergren C, et al. Among authors: lennernas h. Clin Pharmacol Ther. 2003 Nov;74(5):423-36. doi: 10.1016/S0009-9236(03)00238-8. Clin Pharmacol Ther. 2003. PMID: 14586383 Clinical Trial.

3

St John's wort decreases the bioavailability of R- and S-verapamil through induction of the first-pass metabolism.

Tannergren C, Engman H, Knutson L, Hedeland M, Bondesson U, Lennernäs H. Tannergren C, et al. Among authors: lennernas h. Clin Pharmacol Ther. 2004 Apr;75(4):298-309. doi: 10.1016/j.clpt.2003.12.012. Clin Pharmacol Ther. 2004. PMID: 15060508 Clinical Trial.

4

Simultaneous quantification of the enantiomers of verapamil and its N-demethylated metabolite in human plasma using liquid chromatography-tandem mass spectrometry.

Hedeland M, Fredriksson E, Lennernäs H, Bondesson U. Hedeland M, et al. Among authors: lennernas h. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 May 25;804(2):303-11. doi: 10.1016/j.jchromb.2004.01.026. J Chromatogr B Analyt Technol Biomed Life Sci. 2004. PMID: 15081924

5

Effect of erythromycin on the absorption of fexofenadine in the jejunum, ileum and colon determined using local intubation in healthy volunteers.

Petri N, Borga O, Nyberg L, Hedeland M, Bondesson U, Lennernas H. Petri N, et al. Among authors: lennernas h. Int J Clin Pharmacol Ther. 2006 Feb;44(2):71-9. doi: 10.5414/cpp44071. Int J Clin Pharmacol Ther. 2006. PMID: 16502766 Clinical Trial.

6

Flutamide metabolism in four different species in vitro and identification of flutamide metabolites in human patient urine by high performance liquid chromatography/tandem mass spectrometry.

Tevell A, Lennernäs H, Jönsson M, Norlin M, Lennernäs B, Bondesson U, Hedeland M. Tevell A, et al. Among authors: lennernas h, lennernas b. Drug Metab Dispos. 2006 Jun;34(6):984-92. doi: 10.1124/dmd.105.008516. Epub 2006 Mar 15. Drug Metab Dispos. 2006. PMID: 16540588 Clinical Trial.

7

First-pass effects of verapamil on the intestinal absorption and liver disposition of fexofenadine in the porcine model.

Petri N, Bergman E, Forsell P, Hedeland M, Bondesson U, Knutson L, Lennernäs H. Petri N, et al. Among authors: lennernas h. Drug Metab Dispos. 2006 Jul;34(7):1182-9. doi: 10.1124/dmd.105.008409. Epub 2006 Apr 18. Drug Metab Dispos. 2006. PMID: 16621934

8

Biliary secretion of rosuvastatin and bile acids in humans during the absorption phase.

Bergman E, Forsell P, Tevell A, Persson EM, Hedeland M, Bondesson U, Knutson L, Lennernäs H. Bergman E, et al. Among authors: lennernas h. Eur J Pharm Sci. 2006 Nov;29(3-4):205-14. doi: 10.1016/j.ejps.2006.04.015. Epub 2006 May 12. Eur J Pharm Sci. 2006. PMID: 16806856

9

The multiple depletion curves method provides accurate estimates of intrinsic clearance (CLint), maximum velocity of the metabolic reaction (Vmax), and Michaelis constant (Km): accuracy and robustness evaluated through experimental data and Monte Carlo simulations.

Sjögren E, Lennernäs H, Andersson TB, Gråsjö J, Bredberg U. Sjögren E, et al. Among authors: lennernas h. Drug Metab Dispos. 2009 Jan;37(1):47-58. doi: 10.1124/dmd.108.021477. Epub 2008 Sep 29. Drug Metab Dispos. 2009. PMID: 18824525

10

The effect of St. John's wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men.

Lundahl A, Hedeland M, Bondesson U, Knutson L, Lennernäs H. Lundahl A, et al. Among authors: lennernas h. Eur J Pharm Sci. 2009 Mar 2;36(4-5):433-43. doi: 10.1016/j.ejps.2008.11.009. Epub 2008 Nov 27. Eur J Pharm Sci. 2009. PMID: 19073252

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