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Year Number of Results
2020 3
2021 3
2022 2
2023 4
2024 1

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11 results

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Morphing cholinesterase inhibitor amiridine into multipotent drugs for the treatment of Alzheimer's disease.
Mezeiova E, Prchal L, Hrabinova M, Muckova L, Pulkrabkova L, Soukup O, Misiachna A, Janousek J, Fibigar J, Kucera T, Horak M, Makhaeva GF, Korabecny J. Mezeiova E, et al. Among authors: pulkrabkova l. Biomed Pharmacother. 2024 Apr;173:116399. doi: 10.1016/j.biopha.2024.116399. Epub 2024 Mar 15. Biomed Pharmacother. 2024. PMID: 38492439 Free article.
Structure-Guided Design of N-Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease.
Svobodova B, Pulkrabkova L, Panek D, Misiachna A, Kolcheva M, Andrys R, Handl J, Capek J, Nyvltova P, Rousar T, Prchal L, Hepnarova V, Hrabinova M, Muckova L, Tosnerova D, Karabanovich G, Finger V, Soukup O, Horak M, Korabecny J. Svobodova B, et al. Among authors: pulkrabkova l. Int J Mol Sci. 2023 May 23;24(11):9124. doi: 10.3390/ijms24119124. Int J Mol Sci. 2023. PMID: 37298087 Free PMC article.
Highly selective butyrylcholinesterase inhibitors related to Amaryllidaceae alkaloids - Design, synthesis, and biological evaluation.
Pidany F, Kroustkova J, Al Mamun A, Suchankova D, Brazzolotto X, Nachon F, Chantegreil F, Dolezal R, Pulkrabkova L, Muckova L, Hrabinova M, Finger V, Kufa M, Soukup O, Jun D, Jenco J, Kunes J, Novakova L, Korabecny J, Cahlikova L. Pidany F, et al. Among authors: pulkrabkova l. Eur J Med Chem. 2023 Apr 5;252:115301. doi: 10.1016/j.ejmech.2023.115301. Epub 2023 Mar 22. Eur J Med Chem. 2023. PMID: 36996715
Neurotoxicity evoked by organophosphates and available countermeasures.
Pulkrabkova L, Svobodova B, Konecny J, Kobrlova T, Muckova L, Janousek J, Pejchal J, Korabecny J, Soukup O. Pulkrabkova L, et al. Arch Toxicol. 2023 Jan;97(1):39-72. doi: 10.1007/s00204-022-03397-w. Epub 2022 Nov 6. Arch Toxicol. 2023. PMID: 36335468 Review.
N-substituted arylhydroxamic acids as acetylcholinesterase reactivators.
Bondar D, Kapitanov IV, Pulkrabkova L, Soukup O, Jun D, Botelho FD, França TCC, Kuča K, Karpichev Y. Bondar D, et al. Among authors: pulkrabkova l. Chem Biol Interact. 2022 Sep 25;365:110078. doi: 10.1016/j.cbi.2022.110078. Epub 2022 Aug 5. Chem Biol Interact. 2022. PMID: 35940282
Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D2 3,4-dihydroquinolin-2(1H)-one Derivatives Related to Aripiprazole.
Juza R, Stefkova K, Dehaen W, Randakova A, Petrasek T, Vojtechova I, Kobrlova T, Pulkrabkova L, Muckova L, Mecava M, Prchal L, Mezeiova E, Musilek K, Soukup O, Korabecny J. Juza R, et al. Among authors: pulkrabkova l. Biomolecules. 2021 Aug 24;11(9):1262. doi: 10.3390/biom11091262. Biomolecules. 2021. PMID: 34572475 Free PMC article.
Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-d-Aspartate Receptor Antagonists.
Konecny J, Misiachna A, Hrabinova M, Pulkrabkova L, Benkova M, Prchal L, Kucera T, Kobrlova T, Finger V, Kolcheva M, Kortus S, Jun D, Valko M, Horak M, Soukup O, Korabecny J. Konecny J, et al. Among authors: pulkrabkova l. Biomolecules. 2020 Dec 22;11(1):3. doi: 10.3390/biom11010003. Biomolecules. 2020. PMID: 33375115 Free PMC article.
11 results