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Structure-Activity Relationship in Pyrazolo[4,3-c]pyridines, First Inhibitors of PEX14-PEX5 Protein-Protein Interaction with Trypanocidal Activity.
Dawidowski M, Kalel VC, Napolitano V, Fino R, Schorpp K, Emmanouilidis L, Lenhart D, Ostertag M, Kaiser M, Kolonko M, Tippler B, Schliebs W, Dubin G, Mäser P, Tetko IV, Hadian K, Plettenburg O, Erdmann R, Sattler M, Popowicz GM. Dawidowski M, et al. Among authors: lenhart d. J Med Chem. 2020 Jan 23;63(2):847-879. doi: 10.1021/acs.jmedchem.9b01876. Epub 2020 Jan 6. J Med Chem. 2020. PMID: 31860309
Computer-Aided Design and Synthesis of a New Class of PEX14 Inhibitors: Substituted 2,3,4,5-Tetrahydrobenzo[F][1,4]oxazepines as Potential New Trypanocidal Agents.
Fino R, Lenhart D, Kalel VC, Softley CA, Napolitano V, Byrne R, Schliebs W, Dawidowski M, Erdmann R, Sattler M, Schneider G, Plettenburg O, Popowicz GM. Fino R, et al. Among authors: lenhart d. J Chem Inf Model. 2021 Oct 25;61(10):5256-5268. doi: 10.1021/acs.jcim.1c00472. Epub 2021 Oct 1. J Chem Inf Model. 2021. PMID: 34597510 Free article.
Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus.
Kyriakou E, Schmidt S, Dodd GT, Pfuhlmann K, Simonds SE, Lenhart D, Geerlof A, Schriever SC, De Angelis M, Schramm KW, Plettenburg O, Cowley MA, Tiganis T, Tschöp MH, Pfluger PT, Sattler M, Messias AC. Kyriakou E, et al. Among authors: lenhart d. J Med Chem. 2018 Dec 27;61(24):11144-11157. doi: 10.1021/acs.jmedchem.8b01224. Epub 2018 Dec 7. J Med Chem. 2018. PMID: 30525586
Enantioselective catalysis of photochemical reactions.
Brimioulle R, Lenhart D, Maturi MM, Bach T. Brimioulle R, et al. Among authors: lenhart d. Angew Chem Int Ed Engl. 2015 Mar 23;54(13):3872-90. doi: 10.1002/anie.201411409. Epub 2015 Feb 27. Angew Chem Int Ed Engl. 2015. PMID: 25728854
Pentosan Polysulfate Inhibits Attachment and Infection by SARS-CoV-2 In Vitro: Insights into Structural Requirements for Binding.
Bertini S, Alekseeva A, Elli S, Pagani I, Zanzoni S, Eisele G, Krishnan R, Maag KP, Reiter C, Lenhart D, Gruber R, Yates EA, Vicenzi E, Naggi A, Bisio A, Guerrini M. Bertini S, et al. Among authors: lenhart d. Thromb Haemost. 2022 Jun;122(6):984-997. doi: 10.1055/a-1807-0168. Epub 2022 Mar 23. Thromb Haemost. 2022. PMID: 35322395 Free PMC article.
Hemopexin deficiency promotes acute kidney injury in sickle cell disease.
Ofori-Acquah SF, Hazra R, Orikogbo OO, Crosby D, Flage B, Ackah EB, Lenhart D, Tan RJ, Vitturi DA, Paintsil V, Owusu-Dabo E, Ghosh S; SickleGenAfrica Network. Ofori-Acquah SF, et al. Among authors: lenhart d. Blood. 2020 Mar 26;135(13):1044-1048. doi: 10.1182/blood.2019002653. Blood. 2020. PMID: 32043112 Free PMC article.
CT angiography of the hepatic and pancreatic circulation.
Perez-Johnston R, Lenhart DK, Sahani DV. Perez-Johnston R, et al. Among authors: lenhart dk. Radiol Clin North Am. 2010 Mar;48(2):311-30, viii. doi: 10.1016/j.rcl.2010.02.021. Radiol Clin North Am. 2010. PMID: 20609876 Review.
17 results