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Chromatin jets define the properties of cohesin-driven in vivo loop extrusion.
Guo Y, Al-Jibury E, Garcia-Millan R, Ntagiantas K, King JWD, Nash AJ, Galjart N, Lenhard B, Rueckert D, Fisher AG, Pruessner G, Merkenschlager M. Guo Y, et al. Among authors: lenhard b. Mol Cell. 2022 Oct 20;82(20):3769-3780.e5. doi: 10.1016/j.molcel.2022.09.003. Epub 2022 Sep 30. Mol Cell. 2022. PMID: 36182691 Free article.
The DNA-binding protein CTCF limits proximal Vκ recombination and restricts κ enhancer interactions to the immunoglobulin κ light chain locus.
Ribeiro de Almeida C, Stadhouders R, de Bruijn MJ, Bergen IM, Thongjuea S, Lenhard B, van Ijcken W, Grosveld F, Galjart N, Soler E, Hendriks RW. Ribeiro de Almeida C, et al. Among authors: lenhard b. Immunity. 2011 Oct 28;35(4):501-13. doi: 10.1016/j.immuni.2011.07.014. Immunity. 2011. PMID: 22035845 Free article.
The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner.
Sleutels F, Soochit W, Bartkuhn M, Heath H, Dienstbach S, Bergmaier P, Franke V, Rosa-Garrido M, van de Nobelen S, Caesar L, van der Reijden M, Bryne JC, van Ijcken W, Grootegoed JA, Delgado MD, Lenhard B, Renkawitz R, Grosveld F, Galjart N. Sleutels F, et al. Among authors: lenhard b. Epigenetics Chromatin. 2012 Jun 18;5(1):8. doi: 10.1186/1756-8935-5-8. Epigenetics Chromatin. 2012. PMID: 22709888 Free PMC article.
Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation.
Cuartero S, Weiss FD, Dharmalingam G, Guo Y, Ing-Simmons E, Masella S, Robles-Rebollo I, Xiao X, Wang YF, Barozzi I, Djeghloul D, Amano MT, Niskanen H, Petretto E, Dowell RD, Tachibana K, Kaikkonen MU, Nasmyth KA, Lenhard B, Natoli G, Fisher AG, Merkenschlager M. Cuartero S, et al. Among authors: lenhard b. Nat Immunol. 2018 Sep;19(9):932-941. doi: 10.1038/s41590-018-0184-1. Epub 2018 Aug 20. Nat Immunol. 2018. PMID: 30127433 Free PMC article.
Feedforward regulation of Myc coordinates lineage-specific with housekeeping gene expression during B cell progenitor cell differentiation.
Ferreirós-Vidal I, Carroll T, Zhang T, Lagani V, Ramirez RN, Ing-Simmons E, Gómez-Valadés AG, Cooper L, Liang Z, Papoutsoglou G, Dharmalingam G, Guo Y, Tarazona S, Fernandes SJ, Noori P, Silberberg G, Fisher AG, Tsamardinos I, Mortazavi A, Lenhard B, Conesa A, Tegner J, Merkenschlager M, Gomez-Cabrero D. Ferreirós-Vidal I, et al. Among authors: lenhard b. PLoS Biol. 2019 Apr 12;17(4):e2006506. doi: 10.1371/journal.pbio.2006506. eCollection 2019 Apr. PLoS Biol. 2019. PMID: 30978178 Free PMC article.
186 results