Lendrem BC - Search Results

1

How to Ease the Pain of Taking a Diagnostic Point of Care Test to the Market: A Framework for Evidence Development.

Graziadio S, Winter A, Lendrem BC, Suklan J, Jones WS, Urwin SG, O'Leary RA, Dickinson R, Halstead A, Kurowska K, Green K, Sims A, Simpson AJ, Power HM, Allen AJ. Graziadio S, et al. Among authors: lendrem bc. Micromachines (Basel). 2020 Mar 10;11(3):291. doi: 10.3390/mi11030291. Micromachines (Basel). 2020. PMID: 32164393 Free PMC article.

2

Between a ROC and a hard place: Teaching prevalence plots to understand real world biomarker performance in the clinic.

Lendrem BC, Lendrem DW, Pratt AG, Naamane N, McMeekin P, Ng WF, Allen AJ, Power M, Isaacs JD. Lendrem BC, et al. Pharm Stat. 2019 Nov;18(6):632-635. doi: 10.1002/pst.1963. Epub 2019 Jun 23. Pharm Stat. 2019. PMID: 31231892

3

Systematic review of studies investigating ventilator associated pneumonia diagnostics in intensive care.

Al-Omari B, McMeekin P, Allen AJ, Akram AR, Graziadio S, Suklan J, Jones WS, Lendrem BC, Winter A, Cullinan M, Gray J, Dhaliwal K, Walsh TS, Craven TH. Al-Omari B, et al. Among authors: lendrem bc. BMC Pulm Med. 2021 Jun 9;21(1):196. doi: 10.1186/s12890-021-01560-0. BMC Pulm Med. 2021. PMID: 34107929 Free PMC article.

4

Bayesian sample size determination for diagnostic accuracy studies.

Wilson KJ, Williamson SF, Allen AJ, Williams CJ, Hellyer TP, Lendrem BC. Wilson KJ, et al. Among authors: lendrem bc. Stat Med. 2022 Jul 10;41(15):2908-2922. doi: 10.1002/sim.9393. Epub 2022 Apr 10. Stat Med. 2022. PMID: 35403239 Free PMC article.

5

Sample size determination for point-of-care COVID-19 diagnostic tests: a Bayesian approach.

Williamson SF, Williams CJ, Lendrem BC, Wilson KJ. Williamson SF, et al. Among authors: lendrem bc. Diagn Progn Res. 2023 Aug 18;7(1):17. doi: 10.1186/s41512-023-00153-1. Diagn Progn Res. 2023. PMID: 37596684 Free PMC article.

6

Torching the Haystack: modelling fast-fail strategies in drug development.

Lendrem DW, Lendrem BC. Lendrem DW, et al. Among authors: lendrem bc. Drug Discov Today. 2013 Apr;18(7-8):331-6. doi: 10.1016/j.drudis.2012.11.011. Epub 2012 Dec 12. Drug Discov Today. 2013. PMID: 23246516

7

The development speed paradox: can increasing development speed reduce R&D productivity?

Lendrem DW, Lendrem BC. Lendrem DW, et al. Among authors: lendrem bc. Drug Discov Today. 2014 Mar;19(3):209-14. doi: 10.1016/j.drudis.2013.09.002. Epub 2013 Sep 16. Drug Discov Today. 2014. PMID: 24051396

8

R&D productivity rides again?

Lendrem D, Senn SJ, Lendrem BC, Isaacs JD. Lendrem D, et al. Among authors: lendrem bc. Pharm Stat. 2015 Jan-Feb;14(1):1-3. doi: 10.1002/pst.1653. Epub 2014 Oct 22. Pharm Stat. 2015. PMID: 25336017 Review.

9

Progression-seeking bias and rational optimism in research and development.

Lendrem DW, Lendrem BC, Peck RW, Senn SC, Day S, Isaacs JD. Lendrem DW, et al. Among authors: lendrem bc. Nat Rev Drug Discov. 2015 Mar;14(3):219-21. doi: 10.1038/nrd4320-c1. Epub 2015 Feb 6. Nat Rev Drug Discov. 2015. PMID: 25656595 No abstract available.

10

Why is it hard to terminate failing projects in pharmaceutical R&D?

Peck RW, Lendrem DW, Grant I, Lendrem BC, Isaacs JD. Peck RW, et al. Among authors: lendrem bc, lendrem dw. Nat Rev Drug Discov. 2015 Oct;14(10):663-4. doi: 10.1038/nrd4725. Epub 2015 Aug 21. Nat Rev Drug Discov. 2015. PMID: 26294265

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