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Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models.
Frost JL, Le KX, Cynis H, Ekpo E, Kleinschmidt M, Palmour RM, Ervin FR, Snigdha S, Cotman CW, Saido TC, Vassar RJ, St George-Hyslop P, Ikezu T, Schilling S, Demuth HU, Lemere CA. Frost JL, et al. Among authors: lemere ca. Am J Pathol. 2013 Aug;183(2):369-81. doi: 10.1016/j.ajpath.2013.05.005. Epub 2013 Jun 7. Am J Pathol. 2013. PMID: 23747948 Free PMC article.
Effector function of anti-pyroglutamate-3 Aβ antibodies affects cognitive benefit, glial activation and amyloid clearance in Alzheimer's-like mice.
Crehan H, Liu B, Kleinschmidt M, Rahfeld JU, Le KX, Caldarone BJ, Frost JL, Hettmann T, Hutter-Paier B, O'Nuallain B, Park MA, DiCarli MF, Lues I, Schilling S, Lemere CA. Crehan H, et al. Among authors: lemere ca. Alzheimers Res Ther. 2020 Jan 13;12(1):12. doi: 10.1186/s13195-019-0579-8. Alzheimers Res Ther. 2020. PMID: 31931873 Free PMC article.
Focused ultrasound with anti-pGlu3 Aβ enhances efficacy in Alzheimer's disease-like mice via recruitment of peripheral immune cells.
Sun T, Shi Q, Zhang Y, Power C, Hoesch C, Antonelli S, Schroeder MK, Caldarone BJ, Taudte N, Schenk M, Hettmann T, Schilling S, McDannold NJ, Lemere CA. Sun T, et al. Among authors: lemere ca. J Control Release. 2021 Aug 10;336:443-456. doi: 10.1016/j.jconrel.2021.06.037. Epub 2021 Jun 26. J Control Release. 2021. PMID: 34186148 Free PMC article.
Long-Term Sex- and Genotype-Specific Effects of 56Fe Irradiation on Wild-Type and APPswe/PS1dE9 Transgenic Mice.
Schroeder MK, Liu B, Hinshaw RG, Park MA, Wang S, Dubey S, Liu GG, Shi Q, Holton P, Reiser V, Jones PA, Trigg W, Di Carli MF, Caldarone BJ, Williams JP, O'Banion MK, Lemere CA. Schroeder MK, et al. Among authors: lemere ca. Int J Mol Sci. 2021 Dec 10;22(24):13305. doi: 10.3390/ijms222413305. Int J Mol Sci. 2021. PMID: 34948098 Free PMC article.
122 results