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The ligand-bound state of a G protein-coupled receptor stabilizes the interaction of functional cholesterol molecules.
J Lipid Res. 2021;62:100059. doi: 10.1016/j.jlr.2021.100059. Epub 2021 Feb 26.
J Lipid Res. 2021.
PMID: 33647276
Free PMC article.
Functional mapping of the N-terminal arginine cluster and C-terminal acidic residues of Kir6.2 channel fused to a G protein-coupled receptor.
Principalli MA, Lemel L, Rongier A, Godet AC, Langer K, Revilloud J, Darré L, Domene C, Vivaudou M, Moreau CJ.
Principalli MA, et al. Among authors: lemel l.
Biochim Biophys Acta Biomembr. 2017 Oct;1859(10):2144-2153. doi: 10.1016/j.bbamem.2017.07.015. Epub 2017 Jul 28.
Biochim Biophys Acta Biomembr. 2017.
PMID: 28757124
Free PMC article.
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GRKs as Key Modulators of Opioid Receptor Function.
Lemel L, Lane JR, Canals M.
Lemel L, et al.
Cells. 2020 Nov 2;9(11):2400. doi: 10.3390/cells9112400.
Cells. 2020.
PMID: 33147802
Free PMC article.
Review.
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OZITX, a pertussis toxin-like protein for occluding inhibitory G protein signalling including Gαz.
Keen AC, Pedersen MH, Lemel L, Scott DJ, Canals M, Littler DR, Beddoe T, Ono Y, Shi L, Inoue A, Javitch JA, Lane JR.
Keen AC, et al. Among authors: lemel l.
Commun Biol. 2022 Mar 23;5(1):256. doi: 10.1038/s42003-022-03191-5.
Commun Biol. 2022.
PMID: 35322196
Free PMC article.
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Assessment of the potential of novel and classical opioids to induce respiratory depression in mice.
Hill R, Sanchez J, Lemel L, Antonijevic M, Hosking Y, Mistry SN, Kruegel AC, Javitch JA, Lane JR, Canals M.
Hill R, et al. Among authors: lemel l.
Br J Pharmacol. 2023 Dec;180(24):3160-3174. doi: 10.1111/bph.16199. Epub 2023 Aug 22.
Br J Pharmacol. 2023.
PMID: 37489013
Free PMC article.
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Interactions of cholesterol molecules with GPCRs in different states: A comparative analysis of GPCRs' structures.
Moreau CJ, Audic G, Lemel L, García-Fernández MD, Nieścierowicz K.
Moreau CJ, et al. Among authors: lemel l.
Biochim Biophys Acta Biomembr. 2023 Mar;1865(3):184100. doi: 10.1016/j.bbamem.2022.184100. Epub 2022 Dec 12.
Biochim Biophys Acta Biomembr. 2023.
PMID: 36521554
Free article.
Review.
No abstract available.
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