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Discovery of DRP-104, a tumor-targeted metabolic inhibitor prodrug.
Rais R, Lemberg KM, Tenora L, Arwood ML, Pal A, Alt J, Wu Y, Lam J, Aguilar JMH, Zhao L, Peters DE, Tallon C, Pandey R, Thomas AG, Dash RP, Seiwert T, Majer P, Leone RD, Powell JD, Slusher BS. Rais R, et al. Among authors: lemberg km. Sci Adv. 2022 Nov 18;8(46):eabq5925. doi: 10.1126/sciadv.abq5925. Epub 2022 Nov 16. Sci Adv. 2022. PMID: 36383674 Free PMC article.
Clinical development of metabolic inhibitors for oncology.
Lemberg KM, Gori SS, Tsukamoto T, Rais R, Slusher BS. Lemberg KM, et al. J Clin Invest. 2022 Jan 4;132(1):e148550. doi: 10.1172/JCI148550. J Clin Invest. 2022. PMID: 34981784 Free PMC article. Review.
Pro-905, a Novel Purine Antimetabolite, Combines with Glutamine Amidotransferase Inhibition to Suppress Growth of Malignant Peripheral Nerve Sheath Tumor.
Lemberg KM, Ali ES, Krecmerova M, Aguilar JMH, Alt J, Peters DE, Zhao L, Wu Y, Nuha N, Asara JM, Staedtke V, Pratilas CA, Majer P, Rais R, Ben-Sahra I, Slusher BS. Lemberg KM, et al. Mol Cancer Ther. 2023 Dec 1;22(12):1390-1403. doi: 10.1158/1535-7163.MCT-23-0258. Mol Cancer Ther. 2023. PMID: 37616542 Free PMC article.
Trainee-led Engagement of the Care Team Improves Application of an Institutional Blood Culture Clinical Decision Algorithm to Pediatric Oncology Inpatients: A Single-institution Quality Improvement Project.
Lemberg KM, Koontz DW, Young DJ, DiDomizio PG, King A, Chen AR, Gamper CJ, Colantuoni E, Milstone AM, Cooper SL. Lemberg KM, et al. Pediatr Qual Saf. 2022 Mar 30;7(2):e545. doi: 10.1097/pq9.0000000000000545. eCollection 2022 Mar-Apr. Pediatr Qual Saf. 2022. PMID: 35369412 Free PMC article.
16 results