Lejault P - Search Results

1

Identifying G-Quadruplex-DNA-Disrupting Small Molecules.

Mitteaux J, Lejault P, Wojciechowski F, Joubert A, Boudon J, Desbois N, Gros CP, Hudson RHE, Boulé JB, Granzhan A, Monchaud D. Mitteaux J, et al. Among authors: lejault p. J Am Chem Soc. 2021 Aug 18;143(32):12567-12577. doi: 10.1021/jacs.1c04426. Epub 2021 Aug 4. J Am Chem Soc. 2021. PMID: 34346684

2

DNA Junction Ligands Trigger DNA Damage and Are Synthetic Lethal with DNA Repair Inhibitors in Cancer Cells.

Duskova K, Lejault P, Benchimol É, Guillot R, Britton S, Granzhan A, Monchaud D. Duskova K, et al. Among authors: lejault p. J Am Chem Soc. 2020 Jan 8;142(1):424-435. doi: 10.1021/jacs.9b11150. Epub 2019 Dec 20. J Am Chem Soc. 2020. PMID: 31833764

3

How to untie G-quadruplex knots and why?

Lejault P, Mitteaux J, Sperti FR, Monchaud D. Lejault P, et al. Cell Chem Biol. 2021 Apr 15;28(4):436-455. doi: 10.1016/j.chembiol.2021.01.015. Epub 2021 Feb 16. Cell Chem Biol. 2021. PMID: 33596431 Free article. Review.

4

Identifying three-way DNA junction-specific small-molecules.

Vuong S, Stefan L, Lejault P, Rousselin Y, Denat F, Monchaud D. Vuong S, et al. Among authors: lejault p. Biochimie. 2012 Feb;94(2):442-50. doi: 10.1016/j.biochi.2011.08.012. Epub 2011 Aug 25. Biochimie. 2012. PMID: 21884749

5

Small-molecule affinity capture of DNA/RNA quadruplexes and their identification in vitro and in vivo through the G4RP protocol.

Renard I, Grandmougin M, Roux A, Yang SY, Lejault P, Pirrotta M, Wong JMY, Monchaud D. Renard I, et al. Among authors: lejault p. Nucleic Acids Res. 2019 Jun 20;47(11):5502-5510. doi: 10.1093/nar/gkz215. Nucleic Acids Res. 2019. PMID: 30949698 Free PMC article.

6

Biomimetic, Smart, and Multivalent Ligands for G-Quadruplex Isolation and Bioorthogonal Imaging.

Sperti Rota F, Charbonnier T, Lejault P, Zell J, Bernhard C, Valverde IE, Monchaud D. Sperti Rota F, et al. Among authors: lejault p. ACS Chem Biol. 2021 May 21;16(5):905-914. doi: 10.1021/acschembio.1c00111. Epub 2021 Apr 29. ACS Chem Biol. 2021. PMID: 33914525

7

Small-molecule G-quadruplex stabilizers reveal a novel pathway of autophagy regulation in neurons.

Moruno-Manchon JF, Lejault P, Wang Y, McCauley B, Honarpisheh P, Morales Scheihing DA, Singh S, Dang W, Kim N, Urayama A, Zhu L, Monchaud D, McCullough LD, Tsvetkov AS. Moruno-Manchon JF, et al. Among authors: lejault p. Elife. 2020 Feb 11;9:e52283. doi: 10.7554/eLife.52283. Elife. 2020. PMID: 32043463 Free PMC article.

8

Improved performances of catalytic G-quadruplexes (G4-DNAzymes) via the chemical modifications of the DNA backbone to provide G-quadruplexes with double 3'-external G-quartets.

Virgilio A, Esposito V, Lejault P, Monchaud D, Galeone A. Virgilio A, et al. Among authors: lejault p. Int J Biol Macromol. 2020 May 15;151:976-983. doi: 10.1016/j.ijbiomac.2019.10.181. Epub 2019 Nov 17. Int J Biol Macromol. 2020. PMID: 31747569

9

Transcriptome-wide identification of transient RNA G-quadruplexes in human cells.

Yang SY, Lejault P, Chevrier S, Boidot R, Robertson AG, Wong JMY, Monchaud D. Yang SY, et al. Among authors: lejault p. Nat Commun. 2018 Nov 9;9(1):4730. doi: 10.1038/s41467-018-07224-8. Nat Commun. 2018. PMID: 30413703 Free PMC article.

10

Regulation of autophagy by DNA G-quadruplexes.

Lejault P, Moruno-Manchon JF, Vemu SM, Honarpisheh P, Zhu L, Kim N, Urayama A, Monchaud D, McCullough LD, Tsvetkov AS. Lejault P, et al. Autophagy. 2020 Dec;16(12):2252-2259. doi: 10.1080/15548627.2020.1769991. Epub 2020 Jun 10. Autophagy. 2020. PMID: 32420812 Free PMC article.

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