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156 results

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Page 1
Effect of CYP3A4, CYP3A5, MDR1 and POR Genetic Polymorphisms in Immunosuppressive Treatment in Chilean Kidney Transplanted Patients.
Contreras-Castillo S, Plaza A, Stojanova J, Navarro G, Carmona R, Corvalán F, Cerpa L, Sandoval C, Muñoz D, Leiva M, Castañeda LE, Farias N, Alvarez C, Llull G, Mezzano S, Ardiles L, Varela N, Rodríguez MS, Flores C, Cayún JP, Krall P, Quiñones LA. Contreras-Castillo S, et al. Among authors: leiva m. Front Pharmacol. 2021 Dec 6;12:674117. doi: 10.3389/fphar.2021.674117. eCollection 2021. Front Pharmacol. 2021. PMID: 34938174 Free PMC article.
Lack of p38 activation in T cells increases IL-35 and protects against obesity by promoting thermogenesis.
Nikolic I, Ruiz-Garrido I, Crespo M, Romero-Becerra R, Leiva-Vega L, Mora A, León M, Rodríguez E, Leiva M, Plata-Gómez AB, Alvarez Flores MB, Torres JL, Hernández-Cosido L, López JA, Vázquez J, Efeyan A, Martin P, Marcos M, Sabio G. Nikolic I, et al. Among authors: leiva m. EMBO Rep. 2024 May 10. doi: 10.1038/s44319-024-00149-y. Online ahead of print. EMBO Rep. 2024. PMID: 38730210 Free article.
Pembrolizumab or placebo with chemoradiotherapy followed by pembrolizumab or placebo for newly diagnosed, high-risk, locally advanced cervical cancer (ENGOT-cx11/GOG-3047/KEYNOTE-A18): a randomised, double-blind, phase 3 clinical trial.
Lorusso D, Xiang Y, Hasegawa K, Scambia G, Leiva M, Ramos-Elias P, Acevedo A, Sukhin V, Cloven N, Pereira de Santana Gomes AJ, Contreras Mejía F, Reiss A, Ayhan A, Lee JY, Saevets V, Zagouri F, Gilbert L, Sehouli J, Tharavichitkul E, Lindemann K, Lazzari R, Chang CL, Lampé R, Zhu H, Oaknin A, Christiaens M, Polterauer S, Usami T, Li K, Yamada K, Toker S, Keefe SM, Pignata S, Duska LR; ENGOT-cx11/GOG-3047/KEYNOTE-A18 investigators. Lorusso D, et al. Among authors: leiva m. Lancet. 2024 Apr 6;403(10434):1341-1350. doi: 10.1016/S0140-6736(24)00317-9. Epub 2024 Mar 20. Lancet. 2024. PMID: 38521086 Clinical Trial.
p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway.
Fondevila MF, Novoa E, Gonzalez-Rellan MJ, Fernandez U, Heras V, Porteiro B, Parracho T, Dorta V, Riobello C, da Silva Lima N, Seoane S, Garcia-Vence M, Chantada-Vazquez MP, Bravo SB, Senra A, Leiva M, Marcos M, Sabio G, Perez-Fernandez R, Dieguez C, Prevot V, Schwaninger M, Woodhoo A, Martinez-Chantar ML, Schwabe R, Cubero FJ, Varela-Rey M, Crespo J, Iruzubieta P, Nogueiras R. Fondevila MF, et al. Among authors: leiva m. Cell Rep Med. 2024 Feb 20;5(2):101401. doi: 10.1016/j.xcrm.2024.101401. Epub 2024 Feb 9. Cell Rep Med. 2024. PMID: 38340725 Free PMC article.
MCJ: A mitochondrial target for cardiac intervention in pulmonary hypertension.
Santamans AM, Cicuéndez B, Mora A, Villalba-Orero M, Rajlic S, Crespo M, Vo P, Jerome M, Macías Á, López JA, Leiva M, Rocha SF, León M, Rodríguez E, Leiva L, Pintor Chocano A, García Lunar I, García-Álvarez A, Hernansanz-Agustín P, Peinado VI, Barberá JA, Ibañez B, Vázquez J, Spinelli JB, Daiber A, Oliver E, Sabio G. Santamans AM, et al. Among authors: leiva m. Sci Adv. 2024 Jan 19;10(3):eadk6524. doi: 10.1126/sciadv.adk6524. Epub 2024 Jan 19. Sci Adv. 2024. PMID: 38241373 Free PMC article.
Co-Formulation of Recombinant Porcine IL-18 Enhances the Onset of Immune Response in a New Lawsonia intracellularis Vaccine.
Hidalgo-Gajardo A, Gutiérrez N, Lamazares E, Espinoza F, Escobar-Riquelme F, Leiva MJ, Villavicencio C, Mena-Ulecia K, Montesino R, Altamirano C, Sánchez O, Rivas CI, Ruíz Á, Toledo JR. Hidalgo-Gajardo A, et al. Among authors: leiva mj. Vaccines (Basel). 2023 Nov 30;11(12):1788. doi: 10.3390/vaccines11121788. Vaccines (Basel). 2023. PMID: 38140192 Free PMC article.
Durvalumab versus placebo with chemoradiotherapy for locally advanced cervical cancer (CALLA): a randomised, double-blind, phase 3 trial.
Monk BJ, Toita T, Wu X, Vázquez Limón JC, Tarnawski R, Mandai M, Shapira-Frommer R, Mahantshetty U, Del Pilar Estevez-Diz M, Zhou Q, Limaye S, Godinez FJR, Oppermann Kussler C, Varga S, Valdiviezo N, Aoki D, Leiva M, Lee JY, Sulay R, Kreynina Y, Cheng WF, Rey F, Rong Y, Ke G, Wildsmith S, Lloyd A, Dry H, Tablante Nunes A, Mayadev J. Monk BJ, et al. Among authors: leiva m. Lancet Oncol. 2023 Dec;24(12):1334-1348. doi: 10.1016/S1470-2045(23)00479-5. Lancet Oncol. 2023. PMID: 38039991 Clinical Trial.
156 results