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Structural investigation of anti-Trypanosoma cruzi 2-iminothiazolidin-4-ones allows the identification of agents with efficacy in infected mice.
Moreira DR, Costa SP, Hernandes MZ, Rabello MM, de Oliveira Filho GB, de Melo CM, da Rocha LF, de Simone CA, Ferreira RS, Fradico JR, Meira CS, Guimarães ET, Srivastava RM, Pereira VR, Soares MB, Leite AC. Moreira DR, et al. Among authors: leite ac. J Med Chem. 2012 Dec 27;55(24):10918-36. doi: 10.1021/jm301518v. Epub 2012 Dec 7. J Med Chem. 2012. PMID: 23167554
Sulfonamide-metal complexes endowed with potent anti-Trypanosoma cruzi activity.
Chohan ZH, Hernandes MZ, Sensato FR, Moreira DR, Pereira VR, Neves JK, de Oliveira AP, de Oliveira BC, Leite AC. Chohan ZH, et al. Among authors: leite ac. J Enzyme Inhib Med Chem. 2014 Apr;29(2):230-6. doi: 10.3109/14756366.2013.766608. Epub 2013 Feb 25. J Enzyme Inhib Med Chem. 2014. PMID: 23432595
Structural design, synthesis and structure-activity relationships of thiazolidinones with enhanced anti-Trypanosoma cruzi activity.
Moreira DR, Leite AC, Cardoso MV, Srivastava RM, Hernandes MZ, Rabello MM, da Cruz LF, Ferreira RS, de Simone CA, Meira CS, Guimaraes ET, da Silva AC, dos Santos TA, Pereira VR, Soares MB. Moreira DR, et al. Among authors: leite ac. ChemMedChem. 2014 Jan;9(1):177-88. doi: 10.1002/cmdc.201300354. Epub 2013 Nov 7. ChemMedChem. 2014. PMID: 24203393
Design, synthesis and structure-activity relationship of phthalimides endowed with dual antiproliferative and immunomodulatory activities.
Cardoso MV, Moreira DR, Oliveira Filho GB, Cavalcanti SM, Coelho LC, Espíndola JW, Gonzalez LR, Rabello MM, Hernandes MZ, Ferreira PM, Pessoa C, Alberto de Simone C, Guimarães ET, Soares MB, Leite AC. Cardoso MV, et al. Among authors: leite ac. Eur J Med Chem. 2015;96:491-503. doi: 10.1016/j.ejmech.2015.04.041. Epub 2015 Apr 20. Eur J Med Chem. 2015. PMID: 25942060
251 results