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Page 1
Small molecule inhibitors of hantavirus infection.
Hall PR, Leitão A, Ye C, Kilpatrick K, Hjelle B, Oprea TI, Larson RS. Hall PR, et al. Among authors: leitao a. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7085-91. doi: 10.1016/j.bmcl.2010.09.092. Epub 2010 Sep 19. Bioorg Med Chem Lett. 2010. PMID: 20951038 Free PMC article.
Exemestane's 17-hydroxylated metabolite exerts biological effects as an androgen.
Ariazi EA, Leitão A, Oprea TI, Chen B, Louis T, Bertucci AM, Sharma CG, Gill SD, Kim HR, Shupp HA, Pyle JR, Madrack A, Donato AL, Cheng D, Paige JR, Jordan VC. Ariazi EA, et al. Among authors: leitao a. Mol Cancer Ther. 2007 Nov;6(11):2817-27. doi: 10.1158/1535-7163.MCT-07-0312. Epub 2007 Nov 7. Mol Cancer Ther. 2007. PMID: 17989318
In vivo effects of a GPR30 antagonist.
Dennis MK, Burai R, Ramesh C, Petrie WK, Alcon SN, Nayak TK, Bologa CG, Leitao A, Brailoiu E, Deliu E, Dun NJ, Sklar LA, Hathaway HJ, Arterburn JB, Oprea TI, Prossnitz ER. Dennis MK, et al. Among authors: leitao a. Nat Chem Biol. 2009 Jun;5(6):421-7. doi: 10.1038/nchembio.168. Nat Chem Biol. 2009. PMID: 19430488 Free PMC article.
Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt high-throughput flow cytometry system.
Haynes MK, Strouse JJ, Waller A, Leitao A, Curpan RF, Bologa C, Oprea TI, Prossnitz ER, Edwards BS, Sklar LA, Thompson TA. Haynes MK, et al. Among authors: leitao a. J Biomol Screen. 2009 Jul;14(6):596-609. doi: 10.1177/1087057109335671. Epub 2009 May 21. J Biomol Screen. 2009. PMID: 19470718 Free PMC article.
Novel derivatives of 1,3,4-oxadiazoles are potent mitostatic agents featuring strong microtubule depolymerizing activity in the sea urchin embryo and cell culture assays.
Kiselyov AS, Semenova MN, Chernyshova NB, Leitao A, Samet AV, Kislyi KA, Raihstat MM, Oprea T, Lemcke H, Lantow M, Weiss DG, Ikizalp NN, Kuznetsov SA, Semenov VV. Kiselyov AS, et al. Among authors: leitao a. Eur J Med Chem. 2010 May;45(5):1683-97. doi: 10.1016/j.ejmech.2009.12.072. Epub 2010 Jan 14. Eur J Med Chem. 2010. PMID: 20110137
Computational systems chemical biology.
Oprea TI, May EE, Leitão A, Tropsha A. Oprea TI, et al. Among authors: leitao a. Methods Mol Biol. 2011;672:459-88. doi: 10.1007/978-1-60761-839-3_18. Methods Mol Biol. 2011. PMID: 20838980 Free PMC article. Review.
457 results