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Increased uptake of the P2X7 receptor radiotracer 18 F-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice.
Morgan J, Moreno O, Alves M, Baz Z, Menéndez Méndez A, Leister H, Melia C, Smith J, Visekruna A, Nicke A, Bhattacharya A, Ceusters M, Henshall DC, Gómez-Vallejo V, Llop J, Engel T. Morgan J, et al. Among authors: leister h. Epilepsia. 2023 Feb;64(2):511-523. doi: 10.1111/epi.17484. Epub 2022 Dec 27. Epilepsia. 2023. PMID: 36507708 Free PMC article.
Immunoproteasome deficiency results in age-dependent development of epilepsy.
Leister H, Krause FF, Gil B, Prus R, Prus I, Hellhund-Zingel A, Mitra M, Da Rosa Gerbatin R, Delanty N, Beausang A, Brett FM, Farrell MA, Cryan J, O'Brien DF, Henshall DC, Helmprobst F, Pagenstecher A, Steinhoff U, Visekruna A, Engel T. Leister H, et al. Brain Commun. 2024 Jan 29;6(1):fcae017. doi: 10.1093/braincomms/fcae017. eCollection 2024. Brain Commun. 2024. PMID: 38317856 Free PMC article.
Lactate induces metabolic and epigenetic reprogramming of pro-inflammatory Th17 cells.
Lopez Krol A, Nehring HP, Krause FF, Wempe A, Raifer H, Nist A, Stiewe T, Bertrams W, Schmeck B, Luu M, Leister H, Chung HR, Bauer UM, Adhikary T, Visekruna A. Lopez Krol A, et al. Among authors: leister h. EMBO Rep. 2022 Dec 6;23(12):e54685. doi: 10.15252/embr.202254685. Epub 2022 Oct 10. EMBO Rep. 2022. PMID: 36215678 Free PMC article.
Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer.
Luu M, Riester Z, Baldrich A, Reichardt N, Yuille S, Busetti A, Klein M, Wempe A, Leister H, Raifer H, Picard F, Muhammad K, Ohl K, Romero R, Fischer F, Bauer CA, Huber M, Gress TM, Lauth M, Danhof S, Bopp T, Nerreter T, Mulder IE, Steinhoff U, Hudecek M, Visekruna A. Luu M, et al. Among authors: leister h. Nat Commun. 2021 Jul 1;12(1):4077. doi: 10.1038/s41467-021-24331-1. Nat Commun. 2021. PMID: 34210970 Free PMC article.
Selected commensals educate the intestinal vascular and immune system for immunocompetence.
Romero R, Zarzycka A, Preussner M, Fischer F, Hain T, Herrmann JP, Roth K, Keber CU, Suryamohan K, Raifer H, Luu M, Leister H, Bertrams W, Klein M, Shams-Eldin H, Jacob R, Mollenkopf HJ, Rajalingam K, Visekruna A, Steinhoff U. Romero R, et al. Among authors: leister h. Microbiome. 2022 Sep 28;10(1):158. doi: 10.1186/s40168-022-01353-5. Microbiome. 2022. PMID: 36171625 Free PMC article.
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