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Acceptance criteria for new approach methods in toxicology and human health-relevant life science research - part I.
Holzer AK, Dreser N, Pallocca G, Mangerich A, Stacey G, Dipalo M, Van de Water B, Rovida C, Wirtz PH, Van Vugt B, Panzarella G, Hartung T, Terron A, Mangas I, Herzler M, Marx-Stoelting P, Coecke S, Leist M. Holzer AK, et al. Among authors: leist m. ALTEX. 2023;40(4):706-712. doi: 10.14573/altex.2310021. ALTEX. 2023. PMID: 37889190 Free article.
Establishment of a human cell-based in vitro battery to assess developmental neurotoxicity hazard of chemicals.
Blum J, Masjosthusmann S, Bartmann K, Bendt F, Dolde X, Dönmez A, Förster N, Holzer AK, Hübenthal U, Keßel HE, Kilic S, Klose J, Pahl M, Stürzl LC, Mangas I, Terron A, Crofton KM, Scholze M, Mosig A, Leist M, Fritsche E. Blum J, et al. Among authors: leist m. Chemosphere. 2023 Jan;311(Pt 2):137035. doi: 10.1016/j.chemosphere.2022.137035. Epub 2022 Oct 31. Chemosphere. 2023. PMID: 36328314 Free article.
The Current Status and Work of Three Rs Centres and Platforms in Europe.
Neuhaus W, Reininger-Gutmann B, Rinner B, Plasenzotti R, Wilflingseder D, De Kock J, Vanhaecke T, Rogiers V, Jírová D, Kejlová K, Knudsen LE, Nielsen RN, Kleuser B, Kral V, Thöne-Reineke C, Hartung T, Pallocca G, Rovida C, Leist M, Hippenstiel S, Lang A, Retter I, Krämer S, Jedlicka P, Ameli K, Fritsche E, Tigges J, Kuchovská E, Buettner M, Bleich A, Baumgart N, Baumgart J, Meinhardt MW, Spanagel R, Chourbaji S, Kränzlin B, Seeger B, von Köckritz-Blickwede M, Sánchez-Morgado JM, Galligioni V, Ruiz-Pérez D, Movia D, Prina-Mello A, Ahluwalia A, Chiono V, Gutleb AC, Schmit M, van Golen B, van Weereld L, Kienhuis A, van Oort E, van der Valk J, Smith A, Roszak J, Stępnik M, Sobańska Z, Reszka E, Olsson IAS, Franco NH, Sevastre B, Kandarova H, Capdevila S, Johansson J, Svensk E, Cederroth CR, Sandström J, Ragan I, Bubalo N, Kurreck J, Spielmann H. Neuhaus W, et al. Among authors: leist m. Altern Lab Anim. 2022 Nov;50(6):381-413. doi: 10.1177/02611929221140909. Altern Lab Anim. 2022. PMID: 36458800 Review.
Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models.
Capinha L, Zhang Y, Holzer AK, Ückert AK, Zana M, Carta G, Murphy C, Baldovini J, Mazidi Z, Grillari J, Dinnyes A, van de Water B, Leist M, Commandeur JNM, Jennings P. Capinha L, et al. Among authors: leist m. Arch Toxicol. 2023 Feb;97(2):523-545. doi: 10.1007/s00204-022-03436-6. Epub 2022 Dec 28. Arch Toxicol. 2023. PMID: 36576512 Free PMC article.
G × E interactions as a basis for toxicological uncertainty.
Suciu I, Pamies D, Peruzzo R, Wirtz PH, Smirnova L, Pallocca G, Hauck C, Cronin MTD, Hengstler JG, Brunner T, Hartung T, Amelio I, Leist M. Suciu I, et al. Among authors: leist m. Arch Toxicol. 2023 Jul;97(7):2035-2049. doi: 10.1007/s00204-023-03500-9. Epub 2023 Jun 1. Arch Toxicol. 2023. PMID: 37258688 Free PMC article.
New approach methodologies in human regulatory toxicology - Not if, but how and when!
Schmeisser S, Miccoli A, von Bergen M, Berggren E, Braeuning A, Busch W, Desaintes C, Gourmelon A, Grafström R, Harrill J, Hartung T, Herzler M, Kass GEN, Kleinstreuer N, Leist M, Luijten M, Marx-Stoelting P, Poetz O, van Ravenzwaay B, Roggeband R, Rogiers V, Roth A, Sanders P, Thomas RS, Marie Vinggaard A, Vinken M, van de Water B, Luch A, Tralau T. Schmeisser S, et al. Among authors: leist m. Environ Int. 2023 Aug;178:108082. doi: 10.1016/j.envint.2023.108082. Epub 2023 Jul 4. Environ Int. 2023. PMID: 37422975 Free article. Review.
Basic concepts of mixture toxicity and relevance for risk evaluation and regulation.
Bloch D, Diel P, Epe B, Hellwig M, Lampen A, Mally A, Marko D, Villar Fernández MA, Guth S, Roth A, Marchan R, Ghallab A, Cadenas C, Nell P, Vartak N, van Thriel C, Luch A, Schmeisser S, Herzler M, Landsiedel R, Leist M, Marx-Stoelting P, Tralau T, Hengstler JG. Bloch D, et al. Among authors: leist m. Arch Toxicol. 2023 Nov;97(11):3005-3017. doi: 10.1007/s00204-023-03565-6. Epub 2023 Aug 24. Arch Toxicol. 2023. PMID: 37615677 Free PMC article. Review.
394 results