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Derivatives of erythropoietin that are tissue protective but not erythropoietic.
Leist M, Ghezzi P, Grasso G, Bianchi R, Villa P, Fratelli M, Savino C, Bianchi M, Nielsen J, Gerwien J, Kallunki P, Larsen AK, Helboe L, Christensen S, Pedersen LO, Nielsen M, Torup L, Sager T, Sfacteria A, Erbayraktar S, Erbayraktar Z, Gokmen N, Yilmaz O, Cerami-Hand C, Xie QW, Coleman T, Cerami A, Brines M. Leist M, et al. Science. 2004 Jul 9;305(5681):239-42. doi: 10.1126/science.1098313. Science. 2004. PMID: 15247477
Increased erythropoietin production after myocardial infarction in mice.
Mengozzi M, Latini R, Salio M, Sfacteria A, Piedimonte G, Gerwien JG, Leist M, Siren AL, Ghezzi P, Chimenti S. Mengozzi M, et al. Among authors: leist m. Heart. 2006 Jun;92(6):838-9. doi: 10.1136/hrt.2005.064105. Heart. 2006. PMID: 16698839 Free PMC article. No abstract available.
Erythropoietin: not just about erythropoiesis.
Ghezzi P, Bernaudin M, Bianchi R, Blomgren K, Brines M, Campana W, Cavaletti G, Cerami A, Chopp M, Coleman T, Digicaylioglu M, Ehrenreich H, Erbayraktar S, Erbayraktar Z, Gassmann M, Genc S, Gokmen N, Grasso G, Juul S, Lipton SA, Hand CC, Latini R, Lauria G, Leist M, Newton SS, Petit E, Probert L, Sfacteria A, Siren AL, Talan M, Thiemermann C, Westenbrink D, Yaqoob M, Zhu C. Ghezzi P, et al. Among authors: leist m. Lancet. 2010 Jun 19;375(9732):2142. doi: 10.1016/S0140-6736(10)60992-0. Lancet. 2010. PMID: 20609950 Free PMC article. No abstract available.
Asialoerythropoietin is a nonerythropoietic cytokine with broad neuroprotective activity in vivo.
Erbayraktar S, Grasso G, Sfacteria A, Xie QW, Coleman T, Kreilgaard M, Torup L, Sager T, Erbayraktar Z, Gokmen N, Yilmaz O, Ghezzi P, Villa P, Fratelli M, Casagrande S, Leist M, Helboe L, Gerwein J, Christensen S, Geist MA, Pedersen LØ, Cerami-Hand C, Wuerth JP, Cerami A, Brines M. Erbayraktar S, et al. Among authors: leist m. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6741-6. doi: 10.1073/pnas.1031753100. Epub 2003 May 13. Proc Natl Acad Sci U S A. 2003. PMID: 12746497 Free PMC article.
394 results