Leinonen HM - Search Results

1

Corrigendum: Optimized riboswitch-regulated AAV vector for VEGF-B gene therapy.

Eriksson RAE, Nieminen T, Galibert L, Peltola SK, Tikkanen P, Käyhty P, Leinonen HM, Oruetxebarria I, Lepola S, Valkama AJ, Lipponen EM, Lesch HP, Ylä-Herttuala S, Airenne KJ. Eriksson RAE, et al. Among authors: leinonen hm. Front Med (Lausanne). 2023 Mar 3;10:1143748. doi: 10.3389/fmed.2023.1143748. eCollection 2023. Front Med (Lausanne). 2023. PMID: 36936246 Free PMC article.

2

Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease.

Kanninen K, Heikkinen R, Malm T, Rolova T, Kuhmonen S, Leinonen H, Ylä-Herttuala S, Tanila H, Levonen AL, Koistinaho M, Koistinaho J. Kanninen K, et al. Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16505-10. doi: 10.1073/pnas.0908397106. Epub 2009 Sep 10. Proc Natl Acad Sci U S A. 2009. PMID: 19805328 Free PMC article.

3

Cytochrome P450 2A5 constitutive expression and induction by heavy metals is dependent on redox-sensitive transcription factor Nrf2 in liver.

Lämsä V, Levonen AL, Leinonen H, Ylä-Herttuala S, Yamamoto M, Hakkola J. Lämsä V, et al. Chem Res Toxicol. 2010 May 17;23(5):977-85. doi: 10.1021/tx100084c. Chem Res Toxicol. 2010. PMID: 20402460

4

Sulforaphane inhibits endothelial lipase expression through NF-κB in endothelial cells.

Kivelä AM, Mäkinen PI, Jyrkkänen HK, Mella-Aho E, Xia Y, Kansanen E, Leinonen H, Verma IM, Ylä-Herttuala S, Levonen AL. Kivelä AM, et al. Atherosclerosis. 2010 Nov;213(1):122-8. doi: 10.1016/j.atherosclerosis.2010.07.015. Epub 2010 Jul 21. Atherosclerosis. 2010. PMID: 20688330

5

Electrophilic nitro-fatty acids activate NRF2 by a KEAP1 cysteine 151-independent mechanism.

Kansanen E, Bonacci G, Schopfer FJ, Kuosmanen SM, Tong KI, Leinonen H, Woodcock SR, Yamamoto M, Carlberg C, Ylä-Herttuala S, Freeman BA, Levonen AL. Kansanen E, et al. J Biol Chem. 2011 Apr 22;286(16):14019-27. doi: 10.1074/jbc.M110.190710. Epub 2011 Feb 25. J Biol Chem. 2011. PMID: 21357422 Free PMC article.

6

Vascular endothelial growth factor (VEGF)-D stimulates VEGF-A, stanniocalcin-1, and neuropilin-2 and has potent angiogenic effects.

Jauhiainen S, Häkkinen SK, Toivanen PI, Heinonen SE, Jyrkkänen HK, Kansanen E, Leinonen H, Levonen AL, Ylä-Herttuala S. Jauhiainen S, et al. Arterioscler Thromb Vasc Biol. 2011 Jul;31(7):1617-24. doi: 10.1161/ATVBAHA.111.225961. Epub 2011 Apr 7. Arterioscler Thromb Vasc Biol. 2011. PMID: 21474827

7

Novel insights into the regulation of antioxidant-response-element-mediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2.

Jyrkkänen HK, Kuosmanen S, Heinäniemi M, Laitinen H, Kansanen E, Mella-Aho E, Leinonen H, Ylä-Herttuala S, Levonen AL. Jyrkkänen HK, et al. Biochem J. 2011 Dec 1;440(2):167-74. doi: 10.1042/BJ20110526. Biochem J. 2011. PMID: 21812759

8

Oxidative stress-regulated lentiviral TK/GCV gene therapy for lung cancer treatment.

Leinonen HM, Ruotsalainen AK, Määttä AM, Laitinen HM, Kuosmanen SM, Kansanen E, Pikkarainen JT, Lappalainen JP, Samaranayake H, Lesch HP, Kaikkonen MU, Ylä-Herttuala S, Levonen AL. Leinonen HM, et al. Cancer Res. 2012 Dec 1;72(23):6227-35. doi: 10.1158/0008-5472.CAN-12-1166. Epub 2012 Oct 4. Cancer Res. 2012. PMID: 23041549

9

Optimization of lentiviral vector production for scale-up in fixed-bed bioreactor.

Valkama AJ, Leinonen HM, Lipponen EM, Turkki V, Malinen J, Heikura T, Ylä-Herttuala S, Lesch HP. Valkama AJ, et al. Among authors: leinonen hm. Gene Ther. 2018 Jan;25(1):39-46. doi: 10.1038/gt.2017.91. Epub 2017 Oct 5. Gene Ther. 2018. PMID: 29345252 Free PMC article.

10

Preclinical Proof-of-Concept, Analytical Development, and Commercial Scale Production of Lentiviral Vector in Adherent Cells.

Leinonen HM, Lipponen EM, Valkama AJ, Hynynen H, Oruetxebarria I, Turkki V, Olsson V, Kurkipuro J, Samaranayake H, Määttä AM, Parker NR, Ylä-Herttuala S, Lesch HP. Leinonen HM, et al. Mol Ther Methods Clin Dev. 2019 Aug 29;15:63-71. doi: 10.1016/j.omtm.2019.08.006. eCollection 2019 Dec 13. Mol Ther Methods Clin Dev. 2019. PMID: 31649956 Free PMC article.

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