Lei X - Search Results

1

A small-molecule cocktail promotes mammalian cardiomyocyte proliferation and heart regeneration.

Du J, Zheng L, Gao P, Yang H, Yang WJ, Guo F, Liang R, Feng M, Wang Z, Zhang Z, Bai L, Bu Y, Xing S, Zheng W, Wang X, Quan L, Hu X, Wu H, Chen Z, Chen L, Wei K, Zhang Z, Zhu X, Zhang X, Tu Q, Zhao SM, Lei X, Xiong JW. Du J, et al. Among authors: lei x. Cell Stem Cell. 2022 Apr 7;29(4):545-558.e13. doi: 10.1016/j.stem.2022.03.009. Cell Stem Cell. 2022. PMID: 35395187 Free article.

2

Click-based amplification: designed to facilitate various target labelling modes with ultralow background amplification.

Bai J, Guo F, Li M, Li Y, Lei X. Bai J, et al. Among authors: lei x. RSC Chem Biol. 2021 Mar 20;2(3):906-916. doi: 10.1039/d1cb00002k. eCollection 2021 Jun 1. RSC Chem Biol. 2021. PMID: 34458817 Free PMC article.

3

Novel CaMKII-δ Inhibitor Hesperadin Exerts Dual Functions to Ameliorate Cardiac Ischemia/Reperfusion Injury and Inhibit Tumor Growth.

Zhang J, Liang R, Wang K, Zhang W, Zhang M, Jin L, Xie P, Zheng W, Shang H, Hu Q, Li J, Chen G, Wu F, Lan F, Wang L, Wang SQ, Li Y, Zhang Y, Liu J, Lv F, Hu X, Xiao RP, Lei X, Zhang Y. Zhang J, et al. Among authors: lei x. Circulation. 2022 Apr 12;145(15):1154-1168. doi: 10.1161/CIRCULATIONAHA.121.055920. Epub 2022 Mar 23. Circulation. 2022. PMID: 35317609 Free article.

4

Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry.

Wei T, Wang J, Liang R, Chen W, Chen Y, Ma M, He A, Du Y, Zhou W, Zhang Z, Zeng X, Wang C, Lu J, Guo X, Chen XW, Wang Y, Tian R, Xiao J, Lei X. Wei T, et al. Among authors: lei x. Elife. 2022 Apr 19;11:e77696. doi: 10.7554/eLife.77696. Elife. 2022. PMID: 35439114 Free PMC article.

5

Perturbation of biological processes with small molecule kinase inhibitors.

Li W, Wang J, Liang R, Lei X. Li W, et al. Among authors: lei x. Curr Opin Chem Biol. 2022 Oct;70:102185. doi: 10.1016/j.cbpa.2022.102185. Epub 2022 Jul 16. Curr Opin Chem Biol. 2022. PMID: 35853282 Review.

6

Structural basis of TRPV3 inhibition by an antagonist.

Fan J, Hu L, Yue Z, Liao D, Guo F, Ke H, Jiang D, Yang Y, Lei X. Fan J, et al. Among authors: lei x. Nat Chem Biol. 2023 Jan;19(1):81-90. doi: 10.1038/s41589-022-01166-5. Epub 2022 Oct 27. Nat Chem Biol. 2023. PMID: 36302896

7

Structural insights into the covalent regulation of PAPP-A activity by proMBP and STC2.

Zhong Q, Chu H, Wang G, Zhang C, Li R, Guo F, Meng X, Lei X, Zhou Y, Ren R, Tao L, Li N, Gao N, Wei Y, Qiao J, Hang J. Zhong Q, et al. Among authors: lei x. Cell Discov. 2022 Dec 22;8(1):137. doi: 10.1038/s41421-022-00502-2. Cell Discov. 2022. PMID: 36550107 Free PMC article.

8

Natural Product 2-Oxokolavenol Is a Novel FXR Agonist.

Guo F, Gao Y, Li X, Lei X. Guo F, et al. Among authors: lei x. Molecules. 2022 Dec 16;27(24):8968. doi: 10.3390/molecules27248968. Molecules. 2022. PMID: 36558100 Free PMC article.

9

Biomimetic Total Synthesis and the Biological Evaluation of Natural Product (-)-Fargesone A as a Novel FXR Agonist.

Guo F, Chen K, Dong H, Hu D, Gao Y, Liu C, Laphookhieo S, Lei X. Guo F, et al. Among authors: lei x. JACS Au. 2022 Dec 7;2(12):2830-2838. doi: 10.1021/jacsau.2c00600. eCollection 2022 Dec 26. JACS Au. 2022. PMID: 36590256 Free PMC article.

10

Polycarcin V induces DNA-damage response and enables the profiling of DNA-binding proteins.

Yue Z, Wu F, Guo F, Park J, Wang J, Zhang L, Liao D, Li W, Schärer OD, Lei X. Yue Z, et al. Among authors: lei x. Natl Sci Rev. 2022 Mar 11;9(11):nwac046. doi: 10.1093/nsr/nwac046. eCollection 2022 Nov. Natl Sci Rev. 2022. PMID: 36601137 Free PMC article.

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