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Inhibition of the function of class IIa HDACs by blocking their interaction with MEF2.
Jayathilaka N, Han A, Gaffney KJ, Dey R, Jarusiewicz JA, Noridomi K, Philips MA, Lei X, He J, Ye J, Gao T, Petasis NA, Chen L. Jayathilaka N, et al. Among authors: lei x. Nucleic Acids Res. 2012 Jul;40(12):5378-88. doi: 10.1093/nar/gks189. Epub 2012 Mar 6. Nucleic Acids Res. 2012. PMID: 22396528 Free PMC article.
Reversal of pathological cardiac hypertrophy via the MEF2-coregulator interface.
Wei J, Joshi S, Speransky S, Crowley C, Jayathilaka N, Lei X, Wu Y, Gai D, Jain S, Hoosien M, Gao Y, Chen L, Bishopric NH. Wei J, et al. Among authors: lei x. JCI Insight. 2017 Sep 7;2(17):e91068. doi: 10.1172/jci.insight.91068. eCollection 2017 Sep 7. JCI Insight. 2017. PMID: 28878124 Free PMC article.
Deamidation Shunts RelA from Mediating Inflammation to Aerobic Glycolysis.
Zhao J, Tian M, Zhang S, Delfarah A, Gao R, Rao Y, Savas AC, Lu A, Bubb L, Lei X, Moshirian R, Zhu W, Peng C, Jiang T, Chen L, Graham NA, Feng P. Zhao J, et al. Among authors: lei x. Cell Metab. 2020 May 5;31(5):937-955.e7. doi: 10.1016/j.cmet.2020.04.006. Epub 2020 Apr 22. Cell Metab. 2020. PMID: 32325032 Free PMC article.
4,465 results