Lei S - Search Results

1

Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation.

Clark LJ, Krieger J, White AD, Bondarenko V, Lei S, Fang F, Lee JY, Doruker P, Böttke T, Jean-Alphonse F, Tang P, Gardella TJ, Xiao K, Sutkeviciute I, Coin I, Bahar I, Vilardaga JP. Clark LJ, et al. Among authors: lei s. Nat Chem Biol. 2020 Oct;16(10):1096-1104. doi: 10.1038/s41589-020-0567-0. Epub 2020 Jul 6. Nat Chem Biol. 2020. PMID: 32632293 Free PMC article.

2

Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation.

White AD, Peña KA, Clark LJ, Maria CS, Liu S, Jean-Alphonse FG, Lee JY, Lei S, Cheng Z, Tu CL, Fang F, Szeto N, Gardella TJ, Xiao K, Gellman SH, Bahar I, Sutkeviciute I, Chang W, Vilardaga JP. White AD, et al. Among authors: lei s. Sci Signal. 2021 Oct 5;14(703):eabc5944. doi: 10.1126/scisignal.abc5944. Epub 2021 Oct 5. Sci Signal. 2021. PMID: 34609896 Free PMC article.

3

Precise druggability of the PTH type 1 receptor.

Sutkeviciute I, Lee JY, White AD, Maria CS, Peña KA, Savransky S, Doruker P, Li H, Lei S, Kaynak B, Tu C, Clark LJ, Sanker S, Gardella TJ, Chang W, Bahar I, Vilardaga JP. Sutkeviciute I, et al. Among authors: lei s. Nat Chem Biol. 2022 Mar;18(3):272-280. doi: 10.1038/s41589-021-00929-w. Epub 2021 Dec 23. Nat Chem Biol. 2022. PMID: 34949836 Free PMC article.

4

A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds.

Lipton SA, Choi YB, Pan ZH, Lei SZ, Chen HS, Sucher NJ, Loscalzo J, Singel DJ, Stamler JS. Lipton SA, et al. Among authors: lei sz. Nature. 1993 Aug 12;364(6438):626-32. doi: 10.1038/364626a0. Nature. 1993. PMID: 8394509

5

Blockade of NMDA receptor-mediated mobilization of intracellular Ca2+ prevents neurotoxicity.

Lei SZ, Zhang D, Abele AE, Lipton SA. Lei SZ, et al. Brain Res. 1992 Dec 11;598(1-2):196-202. doi: 10.1016/0006-8993(92)90183-a. Brain Res. 1992. PMID: 1486480

6

Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex.

Lei SZ, Pan ZH, Aggarwal SK, Chen HS, Hartman J, Sucher NJ, Lipton SA. Lei SZ, et al. Neuron. 1992 Jun;8(6):1087-99. doi: 10.1016/0896-6273(92)90130-6. Neuron. 1992. PMID: 1376999

7

Sevoflurane blocks KLF5-mediated transcriptional activation of ITGB2 to inhibit macrophage infiltration in hepatic ischemia/reperfusion injury.

Li Y, Gao W, Lei S, Wu X, Yuan T, Ma K, Chi K. Li Y, et al. Among authors: lei s. J Gene Med. 2024 May;26(5):e3692. doi: 10.1002/jgm.3692. J Gene Med. 2024. PMID: 38745073

8

Global trends in pharmacovigilance-related events: a 30-year analysis from the 2019 global burden of disease study.

Lin S, Lei S, Liu W, Zhu X, Yin L, Liu Q, Feng B. Lin S, et al. Among authors: lei s. Int J Clin Pharm. 2024 May 10. doi: 10.1007/s11096-024-01738-6. Online ahead of print. Int J Clin Pharm. 2024. PMID: 38727779

9

A protoplast-based transient gene expression assay for the identification of heat and oxidative stress-regulatory genes in perennial ryegrass.

Lei S, Zhu Y, Jia W, Zhang J, Chi Y, Xu B. Lei S, et al. Plant Methods. 2024 May 9;20(1):67. doi: 10.1186/s13007-024-01192-5. Plant Methods. 2024. PMID: 38725058 Free PMC article.

10

Catalytic Intramolecular Ketone Haloacylation Enabled Stereoselective Heterolytic Cleavage of Cyclopropyl Ketones with Enhanced Reactivity and Regioselectivity beyond Electronics.

Lei S, Wang H, Wang SR. Lei S, et al. Org Lett. 2024 May 8. doi: 10.1021/acs.orglett.4c01241. Online ahead of print. Org Lett. 2024. PMID: 38717836

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