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An activity-based functional test for identifying homologous recombination deficiencies across cancer types in real time.
Cell Rep Med. 2023 Nov 21;4(11):101247. doi: 10.1016/j.xcrm.2023.101247. Epub 2023 Oct 19.
Cell Rep Med. 2023.
PMID: 37863059
Free PMC article.
Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent-strand DNA.
Lyu X, Lei KH, Biak Sang P, Shiva O, Chastain M, Chi P, Chai W.
Lyu X, et al. Among authors: lei kh.
EMBO J. 2021 Jan 15;40(2):e103654. doi: 10.15252/embj.2019103654. Epub 2020 Nov 19.
EMBO J. 2021.
PMID: 33210317
Free PMC article.
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Crosstalk between CST and RPA regulates RAD51 activity during replication stress.
Lei KH, Yang HL, Chang HY, Yeh HY, Nguyen DD, Lee TY, Lyu X, Chastain M, Chai W, Li HW, Chi P.
Lei KH, et al.
Nat Commun. 2021 Nov 5;12(1):6412. doi: 10.1038/s41467-021-26624-x.
Nat Commun. 2021.
PMID: 34741010
Free PMC article.
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Flap endonuclease Rad27 cleaves the RNA of R-loop structures to suppress telomere recombination.
Liu CC, Chan HR, Su GC, Hsieh YZ, Lei KH, Kato T, Yu TY, Kao YW, Cheng TH, Chi P, Lin JJ.
Liu CC, et al. Among authors: lei kh.
Nucleic Acids Res. 2023 May 22;51(9):4398-4414. doi: 10.1093/nar/gkad236.
Nucleic Acids Res. 2023.
PMID: 36999631
Free PMC article.
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RAD51 paralogs synergize with RAD51 to protect reversed forks from cellular nucleases.
Guh CL, Lei KH, Chen YA, Jiang YZ, Chang HY, Liaw H, Li HW, Yen HY, Chi P.
Guh CL, et al. Among authors: lei kh.
Nucleic Acids Res. 2023 Nov 27;51(21):11717-11731. doi: 10.1093/nar/gkad856.
Nucleic Acids Res. 2023.
PMID: 37843130
Free PMC article.
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CaMKK2 and CHK1 phosphorylate human STN1 in response to replication stress to protect stalled forks from aberrant resection.
Jaiswal RK, Lei KH, Chastain M, Wang Y, Shiva O, Li S, You Z, Chi P, Chai W.
Jaiswal RK, et al. Among authors: lei kh.
Nat Commun. 2023 Nov 30;14(1):7882. doi: 10.1038/s41467-023-43685-2.
Nat Commun. 2023.
PMID: 38036565
Free PMC article.
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Effects of sunlight, microbial activity, and temperature on the declines of antibiotic lincomycin in freshwater and saline aquaculture pond waters and sediments.
Lei KH, Lai HT.
Lei KH, et al.
Environ Sci Pollut Res Int. 2019 Nov;26(33):33988-33994. doi: 10.1007/s11356-018-3006-y. Epub 2018 Aug 25.
Environ Sci Pollut Res Int. 2019.
PMID: 30145759
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