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Chemically modified hCFTR mRNAs recuperate lung function in a mouse model of cystic fibrosis.
Haque AKMA, Dewerth A, Antony JS, Riethmüller J, Schweizer GR, Weinmann P, Latifi N, Yasar H, Pedemonte N, Sondo E, Weidensee B, Ralhan A, Laval J, Schlegel P, Seitz C, Loretz B, Lehr CM, Handgretinger R, Kormann MSD. Haque AKMA, et al. Among authors: lehr cm. Sci Rep. 2018 Nov 13;8(1):16776. doi: 10.1038/s41598-018-34960-0. Sci Rep. 2018. PMID: 30425265 Free PMC article.
Cellular delivery of polynucleotides by cationic cyclodextrin polyrotaxanes.
Dandekar P, Jain R, Keil M, Loretz B, Muijs L, Schneider M, Auerbach D, Jung G, Lehr CM, Wenz G. Dandekar P, et al. Among authors: lehr cm. J Control Release. 2012 Dec 28;164(3):387-93. doi: 10.1016/j.jconrel.2012.06.040. Epub 2012 Jul 9. J Control Release. 2012. PMID: 22789529
In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency.
Mahiny AJ, Dewerth A, Mays LE, Alkhaled M, Mothes B, Malaeksefat E, Loretz B, Rottenberger J, Brosch DM, Reautschnig P, Surapolchai P, Zeyer F, Schams A, Carevic M, Bakele M, Griese M, Schwab M, Nürnberg B, Beer-Hammer S, Handgretinger R, Hartl D, Lehr CM, Kormann MS. Mahiny AJ, et al. Among authors: lehr cm. Nat Biotechnol. 2015 Jun;33(6):584-6. doi: 10.1038/nbt.3241. Epub 2015 May 18. Nat Biotechnol. 2015. PMID: 25985262 No abstract available.
384 results