Lehnart SE - Search Results

1

A dual-targeted drug inhibits cardiac ryanodine receptor Ca²⁺ leak but activates SERCA2a Ca²⁺ uptake.

Wegener JW, Mitronova GY, ElShareif L, Quentin C, Belov V, Pochechueva T, Hasenfuss G, Ackermann L, Lehnart SE. Wegener JW, et al. Among authors: lehnart se. Life Sci Alliance. 2023 Nov 27;7(2):e202302278. doi: 10.26508/lsa.202302278. Print 2024 Feb. Life Sci Alliance. 2023. PMID: 38012000 Free PMC article.

2

Remodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacity.

Bellinger AM, Reiken S, Dura M, Murphy PW, Deng SX, Landry DW, Nieman D, Lehnart SE, Samaru M, LaCampagne A, Marks AR. Bellinger AM, et al. Among authors: lehnart se. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2198-202. doi: 10.1073/pnas.0711074105. Epub 2008 Feb 11. Proc Natl Acad Sci U S A. 2008. PMID: 18268335 Free PMC article.

3

Defective ryanodine receptor interdomain interactions may contribute to intracellular Ca2+ leak: a novel therapeutic target in heart failure.

Lehnart SE, Wehrens XH, Marks AR. Lehnart SE, et al. Circulation. 2005 Jun 28;111(25):3342-6. doi: 10.1161/CIRCULATIONAHA.105.551861. Circulation. 2005. PMID: 15983258 Review. No abstract available.

4

Intracellular calcium release and cardiac disease.

Wehrens XH, Lehnart SE, Marks AR. Wehrens XH, et al. Among authors: lehnart se. Annu Rev Physiol. 2005;67:69-98. doi: 10.1146/annurev.physiol.67.040403.114521. Annu Rev Physiol. 2005. PMID: 15709953 Review.

5

Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure.

Wehrens XH, Lehnart SE, Reiken S, van der Nagel R, Morales R, Sun J, Cheng Z, Deng SX, de Windt LJ, Landry DW, Marks AR. Wehrens XH, et al. Among authors: lehnart se. Proc Natl Acad Sci U S A. 2005 Jul 5;102(27):9607-12. doi: 10.1073/pnas.0500353102. Epub 2005 Jun 22. Proc Natl Acad Sci U S A. 2005. PMID: 15972811 Free PMC article.

6

Coronary perfusion cocktails for in vivo gene transfer.

Lehnart SE, Donahue JK. Lehnart SE, et al. Methods Mol Biol. 2003;219:213-8. doi: 10.1385/1-59259-350-x:213. Methods Mol Biol. 2003. PMID: 12597011 No abstract available.

7

Immunophilins and coupled gating of ryanodine receptors.

Lehnart SE, Huang F, Marx SO, Marks AR. Lehnart SE, et al. Curr Top Med Chem. 2003;3(12):1383-91. doi: 10.2174/1568026033451907. Curr Top Med Chem. 2003. PMID: 12871170 Review.

8

Inhibition of extracellular signal-regulated kinase signaling to prevent cardiomyopathy caused by mutation in the gene encoding A-type lamins.

Muchir A, Shan J, Bonne G, Lehnart SE, Worman HJ. Muchir A, et al. Among authors: lehnart se. Hum Mol Genet. 2009 Jan 15;18(2):241-7. doi: 10.1093/hmg/ddn343. Epub 2008 Oct 16. Hum Mol Genet. 2009. PMID: 18927124 Free PMC article.

9

Regulation of ryanodine receptors in the heart.

Lehnart S, Marks AR. Lehnart S, et al. Circ Res. 2007 Oct 12;101(8):746-9. doi: 10.1161/CIRCRESAHA.107.162479. Circ Res. 2007. PMID: 17932330 No abstract available.

10

Arrhythmogenic right ventricular cardiomyopathy in Boxer dogs is associated with calstabin2 deficiency.

Oyama MA, Reiken S, Lehnart SE, Chittur SV, Meurs KM, Stern J, Marks AR. Oyama MA, et al. Among authors: lehnart se. J Vet Cardiol. 2008 Jun;10(1):1-10. doi: 10.1016/j.jvc.2008.04.003. Epub 2008 Jun 2. J Vet Cardiol. 2008. PMID: 18515204 Free PMC article.

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