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An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer's disease.
Jiang Y, Zhou X, Wong HY, Ouyang L, Ip FCF, Chau VMN, Lau SF, Wu W, Wong DYK, Seo H, Fu WY, Lai NCH, Chen Y, Chen Y, Tong EPS; Alzheimer’s Disease Neuroimaging Initiative; Mok VCT, Kwok TCY, Mok KY, Shoai M, Lehallier B, Losada PM, O'Brien E, Porter T, Laws SM, Hardy J, Wyss-Coray T, Masters CL, Fu AKY, Ip NY. Jiang Y, et al. Among authors: lehallier b. Nat Aging. 2022 Jul;2(7):616-634. doi: 10.1038/s43587-022-00241-9. Epub 2022 Jul 15. Nat Aging. 2022. PMID: 37117777 Free PMC article.
Preclinical Assessment of Young Blood Plasma for Alzheimer Disease.
Middeldorp J, Lehallier B, Villeda SA, Miedema SS, Evans E, Czirr E, Zhang H, Luo J, Stan T, Mosher KI, Masliah E, Wyss-Coray T. Middeldorp J, et al. Among authors: lehallier b. JAMA Neurol. 2016 Nov 1;73(11):1325-1333. doi: 10.1001/jamaneurol.2016.3185. JAMA Neurol. 2016. PMID: 27598869 Free PMC article.
Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease.
Gate D, Saligrama N, Leventhal O, Yang AC, Unger MS, Middeldorp J, Chen K, Lehallier B, Channappa D, De Los Santos MB, McBride A, Pluvinage J, Elahi F, Tam GK, Kim Y, Greicius M, Wagner AD, Aigner L, Galasko DR, Davis MM, Wyss-Coray T. Gate D, et al. Among authors: lehallier b. Nature. 2020 Jan;577(7790):399-404. doi: 10.1038/s41586-019-1895-7. Epub 2020 Jan 8. Nature. 2020. PMID: 31915375 Free PMC article.
Exercise plasma boosts memory and dampens brain inflammation via clusterin.
De Miguel Z, Khoury N, Betley MJ, Lehallier B, Willoughby D, Olsson N, Yang AC, Hahn O, Lu N, Vest RT, Bonanno LN, Yerra L, Zhang L, Saw NL, Fairchild JK, Lee D, Zhang H, McAlpine PL, Contrepois K, Shamloo M, Elias JE, Rando TA, Wyss-Coray T. De Miguel Z, et al. Among authors: lehallier b. Nature. 2021 Dec;600(7889):494-499. doi: 10.1038/s41586-021-04183-x. Epub 2021 Dec 8. Nature. 2021. PMID: 34880498 Free PMC article.
A neuronal blood marker is associated with mortality in old age.
Kaeser SA, Lehallier B, Thinggaard M, Häsler LM, Apel A, Bergmann C, Berdnik D, Jeune B, Christensen K, Grönke S, Partridge L, Wyss-Coray T, Mengel-From J, Jucker M. Kaeser SA, et al. Among authors: lehallier b. Nat Aging. 2021 Feb;1(2):218-225. doi: 10.1038/s43587-021-00028-4. Epub 2021 Feb 11. Nat Aging. 2021. PMID: 37118632
Organ aging signatures in the plasma proteome track health and disease.
Oh HS, Rutledge J, Nachun D, Pálovics R, Abiose O, Moran-Losada P, Channappa D, Urey DY, Kim K, Sung YJ, Wang L, Timsina J, Western D, Liu M, Kohlfeld P, Budde J, Wilson EN, Guen Y, Maurer TM, Haney M, Yang AC, He Z, Greicius MD, Andreasson KI, Sathyan S, Weiss EF, Milman S, Barzilai N, Cruchaga C, Wagner AD, Mormino E, Lehallier B, Henderson VW, Longo FM, Montgomery SB, Wyss-Coray T. Oh HS, et al. Among authors: lehallier b. Nature. 2023 Dec;624(7990):164-172. doi: 10.1038/s41586-023-06802-1. Epub 2023 Dec 6. Nature. 2023. PMID: 38057571 Free PMC article.
46 results