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Stem cells living with a Notch.
Koch U, Lehal R, Radtke F. Koch U, et al. Among authors: lehal r. Development. 2013 Feb;140(4):689-704. doi: 10.1242/dev.080614. Development. 2013. PMID: 23362343 Free article. Review.
Pharmacological disruption of the Notch transcription factor complex.
Lehal R, Zaric J, Vigolo M, Urech C, Frismantas V, Zangger N, Cao L, Berger A, Chicote I, Loubéry S, Choi SH, Koch U, Blacklow SC, Palmer HG, Bornhauser B, González-Gaitán M, Arsenijevic Y, Zoete V, Aster JC, Bourquin JP, Radtke F. Lehal R, et al. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16292-16301. doi: 10.1073/pnas.1922606117. Epub 2020 Jun 29. Proc Natl Acad Sci U S A. 2020. PMID: 32601208 Free PMC article.
Notch Inhibition in Cancer: Challenges and Opportunities.
Fabbro D, Bauer M, Murone M, Lehal R. Fabbro D, et al. Among authors: lehal r. Chimia (Aarau). 2020 Oct 28;74(10):779-783. doi: 10.2533/chimia.2020.779. Chimia (Aarau). 2020. PMID: 33115560 Free article.
Gene expression patterns in adenoid cystic carcinoma with and without diffuse NOTCH1 intracellular domain (NICD1) immunohistochemistry staining.
Patel K, Manzo M, Hapuarachi B, Rack S, Jermann P, Feeney L, Heathcote E, Betts G, Aster JC, Murone M, Bobadilla M, Lehal R, Vogl FD, Harrington K, Metcalf R. Patel K, et al. Among authors: lehal r. Oral Oncol. 2023 Nov;146:106542. doi: 10.1016/j.oraloncology.2023.106542. Epub 2023 Aug 22. Oral Oncol. 2023. PMID: 37619521 No abstract available.
CB-103: A novel CSL-NICD inhibitor for the treatment of NOTCH-driven T-cell acute lymphoblastic leukemia: A case report of complete clinical response in a patient with relapsed and refractory T-ALL.
Medinger M, Junker T, Heim D, Tzankov A, Jermann PM, Bobadilla M, Vigolo M, Lehal R, Vogl FD, Bauer M, Passweg J. Medinger M, et al. Among authors: lehal r. EJHaem. 2022 Jun 16;3(3):1009-1012. doi: 10.1002/jha2.510. eCollection 2022 Aug. EJHaem. 2022. PMID: 36051082 Free PMC article.
15 results