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Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining.
Ropars V, Drevet P, Legrand P, Baconnais S, Amram J, Faure G, Márquez JA, Piétrement O, Guerois R, Callebaut I, Le Cam E, Revy P, de Villartay JP, Charbonnier JB. Ropars V, et al. Among authors: legrand p. Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12663-8. doi: 10.1073/pnas.1100758108. Epub 2011 Jul 18. Proc Natl Acad Sci U S A. 2011. PMID: 21768349 Free PMC article.
Dual functions of the Hsm3 protein in chaperoning and scaffolding regulatory particle subunits during the proteasome assembly.
Barrault MB, Richet N, Godard C, Murciano B, Le Tallec B, Rousseau E, Legrand P, Charbonnier JB, Le Du MH, Guérois R, Ochsenbein F, Peyroche A. Barrault MB, et al. Among authors: legrand p. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):E1001-10. doi: 10.1073/pnas.1116538109. Epub 2012 Mar 29. Proc Natl Acad Sci U S A. 2012. PMID: 22460800 Free PMC article.
Structural insight into how the human helicase subunit MCM2 may act as a histone chaperone together with ASF1 at the replication fork.
Richet N, Liu D, Legrand P, Velours C, Corpet A, Gaubert A, Bakail M, Moal-Raisin G, Guerois R, Compper C, Besle A, Guichard B, Almouzni G, Ochsenbein F. Richet N, et al. Among authors: legrand p. Nucleic Acids Res. 2015 Feb 18;43(3):1905-17. doi: 10.1093/nar/gkv021. Epub 2015 Jan 23. Nucleic Acids Res. 2015. PMID: 25618846 Free PMC article.
XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nemoz C, Ropars V, Frit P, Gontier A, Drevet P, Yu J, Guerois R, Pitois A, Comte A, Delteil C, Barboule N, Legrand P, Baconnais S, Yin Y, Tadi S, Barbet-Massin E, Berger I, Le Cam E, Modesti M, Rothenberg E, Calsou P, Charbonnier JB. Nemoz C, et al. Among authors: legrand p. Nat Struct Mol Biol. 2018 Oct;25(10):971-980. doi: 10.1038/s41594-018-0133-6. Epub 2018 Oct 5. Nat Struct Mol Biol. 2018. PMID: 30291363 Free PMC article.
Molecular basis of the dual role of the Mlh1-Mlh3 endonuclease in MMR and in meiotic crossover formation.
Dai J, Sanchez A, Adam C, Ranjha L, Reginato G, Chervy P, Tellier-Lebegue C, Andreani J, Guérois R, Ropars V, Le Du MH, Maloisel L, Martini E, Legrand P, Thureau A, Cejka P, Borde V, Charbonnier JB. Dai J, et al. Among authors: legrand p. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2022704118. doi: 10.1073/pnas.2022704118. Proc Natl Acad Sci U S A. 2021. PMID: 34088835 Free PMC article.
Study of the DnaB:DciA interplay reveals insights into the primary mode of loading of the bacterial replicative helicase.
Marsin S, Adam Y, Cargemel C, Andreani J, Baconnais S, Legrand P, Li de la Sierra-Gallay I, Humbert A, Aumont-Nicaise M, Velours C, Ochsenbein F, Durand D, Le Cam E, Walbott H, Possoz C, Quevillon-Cheruel S, Ferat JL. Marsin S, et al. Among authors: legrand p. Nucleic Acids Res. 2021 Jun 21;49(11):6569-6586. doi: 10.1093/nar/gkab463. Nucleic Acids Res. 2021. PMID: 34107018 Free PMC article.
BRCA2-HSF2BP oligomeric ring disassembly by BRME1 promotes homologous recombination.
Ghouil R, Miron S, Sato K, Ristic D, van Rossum-Fikkert SE, Legrand P, Ouldali M, Winter JM, Ropars V, David G, Arteni AA, Wyman C, Knipscheer P, Kanaar R, Zelensky AN, Zinn-Justin S. Ghouil R, et al. Among authors: legrand p. Sci Adv. 2023 Oct 27;9(43):eadi7352. doi: 10.1126/sciadv.adi7352. Epub 2023 Oct 27. Sci Adv. 2023. PMID: 37889963 Free PMC article.
399 results