Legrand N - Search Results

1

Efficient CRM197-mediated drug targeting to monocytes.

Schenk GJ, Haasnoot PC, Centlivre M, Legrand N, Rip J, de Boer AG, Berkhout B. Schenk GJ, et al. Among authors: legrand n. J Control Release. 2012 Feb 28;158(1):139-47. doi: 10.1016/j.jconrel.2011.09.091. Epub 2011 Oct 1. J Control Release. 2012. PMID: 21982901

2

Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune system (Rag-2(-/-)gammac(-/-)) mouse model.

ter Brake O, Legrand N, von Eije KJ, Centlivre M, Spits H, Weijer K, Blom B, Berkhout B. ter Brake O, et al. Among authors: legrand n. Gene Ther. 2009 Jan;16(1):148-53. doi: 10.1038/gt.2008.124. Epub 2008 Jul 31. Gene Ther. 2009. PMID: 18668146

3

A doxycycline-dependent human immunodeficiency virus type 1 replicates in vivo without inducing CD4+ T-cell depletion.

Legrand N, van der Velden GJ, Fang RHT, Douaisi M, Weijer K, Das AT, Blom B, Uittenbogaart CH, Berkhout B, Centlivre M. Legrand N, et al. J Gen Virol. 2012 Sep;93(Pt 9):2017-2027. doi: 10.1099/vir.0.042796-0. Epub 2012 May 30. J Gen Virol. 2012. PMID: 22647372 Free PMC article.

4

A sensitive cell-based assay to measure the doxycycline concentration in biological samples.

Kleibeuker W, Zhou X, Centlivre M, Legrand N, Page M, Almond N, Berkhout B, Das AT. Kleibeuker W, et al. Among authors: legrand n. Hum Gene Ther. 2009 May;20(5):524-30. doi: 10.1089/hum.2008.182. Hum Gene Ther. 2009. PMID: 19203210

5

Preclinical in vivo evaluation of the safety of a multi-shRNA-based gene therapy against HIV-1.

Centlivre M, Legrand N, Klamer S, Liu YP, Jasmijn von Eije K, Bohne M, Rijnstra ES, Weijer K, Blom B, Voermans C, Spits H, Berkhout B. Centlivre M, et al. Among authors: legrand n. Mol Ther Nucleic Acids. 2013 Sep 3;2(9):e120. doi: 10.1038/mtna.2013.48. Mol Ther Nucleic Acids. 2013. PMID: 24002730 Free PMC article.

6

Altered dynamics and differential infection profiles of lymphoid and myeloid cell subsets during acute and chronic HIV-1 infection.

Centlivre M, Legrand N, Steingrover R, van der Sluis R, Grijsen ML, Bakker M, Jurriaans S, Berkhout B, Paxton WA, Prins JM, Pollakis G. Centlivre M, et al. Among authors: legrand n. J Leukoc Biol. 2011 May;89(5):785-95. doi: 10.1189/jlb.0410231. Epub 2011 Feb 10. J Leukoc Biol. 2011. PMID: 21310820

7

Autoregulatory lentiviral vectors allow multiple cycles of doxycycline-inducible gene expression in human hematopoietic cells in vivo.

Centlivre M, Zhou X, Pouw SM, Weijer K, Kleibeuker W, Das AT, Blom B, Seppen J, Berkhout B, Legrand N. Centlivre M, et al. Among authors: legrand n. Gene Ther. 2010 Jan;17(1):14-25. doi: 10.1038/gt.2009.109. Epub 2009 Sep 3. Gene Ther. 2010. PMID: 19727135

8

In vivo modulation of gene expression by lentiviral transduction in "human immune system" Rag2-/- gamma c -/- mice.

van Lent AU, Centlivre M, Nagasawa M, Karrich JJ, Pouw SM, Weijer K, Spits H, Blom B, Legrand N. van Lent AU, et al. Among authors: legrand n. Methods Mol Biol. 2010;595:87-115. doi: 10.1007/978-1-60761-421-0_6. Methods Mol Biol. 2010. PMID: 19941107

9

Accelerated thymopoiesis and improved T-cell responses in HLA-A2/-DR2 transgenic BRGS-based human immune system mice.

Masse-Ranson G, Dusséaux M, Fiquet O, Darche S, Boussand M, Li Y, Lopez-Lastra S, Legrand N, Corcuff E, Toubert A, Centlivre M, Bruel T, Spits H, Schwartz O, Lévy Y, Strick-Marchand H, Di Santo JP. Masse-Ranson G, et al. Among authors: legrand n. Eur J Immunol. 2019 Jun;49(6):954-965. doi: 10.1002/eji.201848001. Epub 2019 Apr 2. Eur J Immunol. 2019. PMID: 30888052 Free article.

10

Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo.

Legrand N, Huntington ND, Nagasawa M, Bakker AQ, Schotte R, Strick-Marchand H, de Geus SJ, Pouw SM, Böhne M, Voordouw A, Weijer K, Di Santo JP, Spits H. Legrand N, et al. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13224-9. doi: 10.1073/pnas.1101398108. Epub 2011 Jul 25. Proc Natl Acad Sci U S A. 2011. PMID: 21788504 Free PMC article.

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