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Different states of stemness of glioblastoma stem cells sustain glioblastoma subtypes indicating novel clinical biomarkers and high-efficacy customized therapies.
Visioli A, Trivieri N, Mencarelli G, Giani F, Copetti M, Palumbo O, Pracella R, Cariglia MG, Barile C, Mischitelli L, Soriano AA, Palumbo P, Legnani F, DiMeco F, Gorgoglione L, Pesole G, Vescovi AL, Binda E. Visioli A, et al. Among authors: legnani f. J Exp Clin Cancer Res. 2023 Sep 21;42(1):244. doi: 10.1186/s13046-023-02811-0. J Exp Clin Cancer Res. 2023. PMID: 37735434 Free PMC article.
Wnt5a Drives an Invasive Phenotype in Human Glioblastoma Stem-like Cells.
Binda E, Visioli A, Giani F, Trivieri N, Palumbo O, Restelli S, Dezi F, Mazza T, Fusilli C, Legnani F, Carella M, Di Meco F, Duggal R, Vescovi AL. Binda E, et al. Among authors: legnani f. Cancer Res. 2017 Feb 15;77(4):996-1007. doi: 10.1158/0008-5472.CAN-16-1693. Epub 2016 Dec 23. Cancer Res. 2017. PMID: 28011620 Free article.
Growth factor independence underpins a paroxysmal, aggressive Wnt5aHigh/EphA2Low phenotype in glioblastoma stem cells, conducive to experimental combinatorial therapy.
Trivieri N, Visioli A, Mencarelli G, Cariglia MG, Marongiu L, Pracella R, Giani F, Soriano AA, Barile C, Cajola L, Copetti M, Palumbo O, Legnani F, DiMeco F, Gorgoglione L, Vescovi AL, Binda E. Trivieri N, et al. Among authors: legnani f. J Exp Clin Cancer Res. 2022 Apr 12;41(1):139. doi: 10.1186/s13046-022-02333-1. J Exp Clin Cancer Res. 2022. PMID: 35414102 Free PMC article.
Local delivery of hrBMP4 as an anticancer therapy in patients with recurrent glioblastoma: a first-in-human phase 1 dose escalation trial.
Bos EM, Binda E, Verploegh ISC, Wembacher E, Hoefnagel D, Balvers RK, Korporaal AL, Conidi A, Warnert EAH, Trivieri N, Visioli A, Zaccarini P, Caiola L, van Wijck R, van der Spek P, Huylebroeck D, Leenstra S, Lamfers MLM, Ram Z, Westphal M, Noske D, Legnani F, DiMeco F, Vescovi AL, Dirven CMF. Bos EM, et al. Among authors: legnani f. Mol Cancer. 2023 Aug 10;22(1):129. doi: 10.1186/s12943-023-01835-6. Mol Cancer. 2023. PMID: 37563568 Free PMC article. Clinical Trial.
93 results