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Increased reactive oxygen species production and lower abundance of complex I subunits and carnitine palmitoyltransferase 1B protein despite normal mitochondrial respiration in insulin-resistant human skeletal muscle.
Lefort N, Glancy B, Bowen B, Willis WT, Bailowitz Z, De Filippis EA, Brophy C, Meyer C, Højlund K, Yi Z, Mandarino LJ. Lefort N, et al. Diabetes. 2010 Oct;59(10):2444-52. doi: 10.2337/db10-0174. Epub 2010 Aug 3. Diabetes. 2010. PMID: 20682693 Free PMC article.
Regulation of skeletal muscle oxidative capacity and insulin signaling by the mitochondrial rhomboid protease PARL.
Civitarese AE, MacLean PS, Carling S, Kerr-Bayles L, McMillan RP, Pierce A, Becker TC, Moro C, Finlayson J, Lefort N, Newgard CB, Mandarino L, Cefalu W, Walder K, Collier GR, Hulver MW, Smith SR, Ravussin E. Civitarese AE, et al. Among authors: lefort n. Cell Metab. 2010 May 5;11(5):412-26. doi: 10.1016/j.cmet.2010.04.004. Cell Metab. 2010. PMID: 20444421 Free PMC article.
51 results