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Phosphatases control PKA-dependent functional microdomains at the outer mitochondrial membrane.
Burdyga A, Surdo NC, Monterisi S, Di Benedetto G, Grisan F, Penna E, Pellegrini L, Zaccolo M, Bortolozzi M, Swietach P, Pozzan T, Lefkimmiatis K. Burdyga A, et al. Among authors: lefkimmiatis k. Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6497-E6506. doi: 10.1073/pnas.1806318115. Epub 2018 Jun 25. Proc Natl Acad Sci U S A. 2018. PMID: 29941564 Free PMC article.
Mitochondrial communication in the context of aging.
Lefkimmiatis K, Grisan F, Iannucci LF, Surdo NC, Pozzan T, Di Benedetto G. Lefkimmiatis K, et al. Aging Clin Exp Res. 2021 May;33(5):1367-1370. doi: 10.1007/s40520-019-01451-9. Epub 2020 Jan 10. Aging Clin Exp Res. 2021. PMID: 31925726
Compartmentalized Signaling in Aging and Neurodegeneration.
Di Benedetto G, Iannucci LF, Surdo NC, Zanin S, Conca F, Grisan F, Gerbino A, Lefkimmiatis K. Di Benedetto G, et al. Among authors: lefkimmiatis k. Cells. 2021 Feb 22;10(2):464. doi: 10.3390/cells10020464. Cells. 2021. PMID: 33671541 Free PMC article. Review.
PKA compartmentalization links cAMP signaling and autophagy.
Grisan F, Iannucci LF, Surdo NC, Gerbino A, Zanin S, Di Benedetto G, Pozzan T, Lefkimmiatis K. Grisan F, et al. Among authors: lefkimmiatis k. Cell Death Differ. 2021 Aug;28(8):2436-2449. doi: 10.1038/s41418-021-00761-8. Epub 2021 Mar 19. Cell Death Differ. 2021. PMID: 33742135 Free PMC article.
Cyclic AMP induces reversible EPAC1 condensates that regulate histone transcription.
Iannucci LF, D'Erchia AM, Picardi E, Bettio D, Conca F, Surdo NC, Di Benedetto G, Musso D, Arrigoni C, Lolicato M, Vismara M, Grisan F, Salviati L, Milanesi L, Pesole G, Lefkimmiatis K. Iannucci LF, et al. Among authors: lefkimmiatis k. Nat Commun. 2023 Sep 8;14(1):5521. doi: 10.1038/s41467-023-41088-x. Nat Commun. 2023. PMID: 37684224 Free PMC article.
Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2.
Zoccarato A, Surdo NC, Aronsen JM, Fields LA, Mancuso L, Dodoni G, Stangherlin A, Livie C, Jiang H, Sin YY, Gesellchen F, Terrin A, Baillie GS, Nicklin SA, Graham D, Szabo-Fresnais N, Krall J, Vandeput F, Movsesian M, Furlan L, Corsetti V, Hamilton G, Lefkimmiatis K, Sjaastad I, Zaccolo M. Zoccarato A, et al. Among authors: lefkimmiatis k. Circ Res. 2015 Sep 25;117(8):707-19. doi: 10.1161/CIRCRESAHA.114.305892. Epub 2015 Aug 4. Circ Res. 2015. PMID: 26243800 Free article.
The basics of mitochondrial cAMP signalling: Where, when, why.
Di Benedetto G, Lefkimmiatis K, Pozzan T. Di Benedetto G, et al. Among authors: lefkimmiatis k. Cell Calcium. 2021 Jan;93:102320. doi: 10.1016/j.ceca.2020.102320. Epub 2020 Nov 22. Cell Calcium. 2021. PMID: 33296837 Free article. Review.
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