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Targeting PLK1 as a novel chemopreventive approach to eradicate preneoplastic mucosal changes in the head and neck.
de Boer DV, Martens-de Kemp SR, Buijze M, Stigter-van Walsum M, Bloemena E, Dietrich R, Leemans CR, van Beusechem VW, Braakhuis BJM, Brakenhoff RH. de Boer DV, et al. Among authors: leemans cr. Oncotarget. 2017 May 16;8(58):97928-97940. doi: 10.18632/oncotarget.17880. eCollection 2017 Nov 17. Oncotarget. 2017. PMID: 29228663 Free PMC article.
Multiple head and neck tumors frequently originate from a single preneoplastic lesion.
Tabor MP, Brakenhoff RH, Ruijter-Schippers HJ, Van Der Wal JE, Snow GB, Leemans CR, Braakhuis BJ. Tabor MP, et al. Among authors: leemans cr. Am J Pathol. 2002 Sep;161(3):1051-60. doi: 10.1016/S0002-9440(10)64266-6. Am J Pathol. 2002. PMID: 12213734 Free PMC article.
Previously, we detected genetically altered and tumor-related mucosal lesions in the resection margins in 25% of unselected head and neck squamous cell carcinoma patients (Tabor MP, Brakenhoff RH, van Houten VMM, Kummer JA, Snel MHJ, Snijders PJF, Snow GB, Leemans CR …
Previously, we detected genetically altered and tumor-related mucosal lesions in the resection margins in 25% of unselected head and neck sq …
505 results