Leedham SJ - Search Results

1

Bone Morphogenetic Protein Pathway Antagonism by Grem1 Regulates Epithelial Cell Fate in Intestinal Regeneration.

Koppens MAJ, Davis H, Valbuena GN, Mulholland EJ, Nasreddin N, Colombe M, Antanaviciute A, Biswas S, Friedrich M, Lee L; Oxford IBD Cohort Investigators; Wang LM, Koelzer VH, East JE, Simmons A, Winton DJ, Leedham SJ. Koppens MAJ, et al. Among authors: leedham sj. Gastroenterology. 2021 Jul;161(1):239-254.e9. doi: 10.1053/j.gastro.2021.03.052. Epub 2021 Apr 2. Gastroenterology. 2021. PMID: 33819486 Free PMC article.

2

Intestinal stem cells.

Leedham SJ, Brittan M, McDonald SA, Wright NA. Leedham SJ, et al. J Cell Mol Med. 2005 Jan-Mar;9(1):11-24. doi: 10.1111/j.1582-4934.2005.tb00333.x. J Cell Mol Med. 2005. PMID: 15784161 Free PMC article. Review.

3

A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts.

Leedham SJ, Rodenas-Cuadrado P, Howarth K, Lewis A, Mallappa S, Segditsas S, Davis H, Jeffery R, Rodriguez-Justo M, Keshav S, Travis SP, Graham TA, East J, Clark S, Tomlinson IP. Leedham SJ, et al. Gut. 2013 Jan;62(1):83-93. doi: 10.1136/gutjnl-2011-301601. Epub 2012 Jan 27. Gut. 2013. PMID: 22287596 Free PMC article.

4

Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1.

Jaeger E, Leedham S, Lewis A, Segditsas S, Becker M, Cuadrado PR, Davis H, Kaur K, Heinimann K, Howarth K; HMPS Collaboration; East J, Taylor J, Thomas H, Tomlinson I. Jaeger E, et al. Nat Genet. 2012 May 6;44(6):699-703. doi: 10.1038/ng.2263. Nat Genet. 2012. PMID: 22561515 Free PMC article.

5

Diagnosis of sessile serrated polyps/adenomas: what does this mean for the pathologist, gastroenterologist and patient?

Leedham S, East JE, Chetty R. Leedham S, et al. J Clin Pathol. 2013 Apr;66(4):265-8. doi: 10.1136/jclinpath-2013-201457. Epub 2013 Feb 12. J Clin Pathol. 2013. PMID: 23404799 Review. No abstract available.

6

Reporting trends of right-sided hyperplastic and sessile serrated polyps in a large teaching hospital over a 4-year period (2009-2012).

Gill P, Wang LM, Bailey A, East JE, Leedham S, Chetty R. Gill P, et al. J Clin Pathol. 2013 Aug;66(8):655-8. doi: 10.1136/jclinpath-2013-201608. Epub 2013 Apr 10. J Clin Pathol. 2013. PMID: 23576460

7

Left-sided sessile serrated polyps/adenomas.

Chetty R, Wang LM, Gill P, East JE, Leedham S. Chetty R, et al. Hum Pathol. 2013 Sep;44(9):1959-60. doi: 10.1016/j.humpath.2013.05.017. Hum Pathol. 2013. PMID: 23969097 No abstract available.

8

Proximal colon cancer and serrated adenomas - hunting the missing 10%.

Gill P, Rafferty H, Munday D, Bailey A, Wang LM, East JE, Chetty R, Leedham SJ. Gill P, et al. Among authors: leedham sj. Clin Med (Lond). 2013 Dec;13(6):557-61. doi: 10.7861/clinmedicine.13-6-557. Clin Med (Lond). 2013. PMID: 24298100 Free PMC article. Review.

9

Colonoscopy, tumors.

East JE, Leedham SJ. East JE, et al. Among authors: leedham sj. Endoscopy. 2014 Apr;46(4):318-21. doi: 10.1055/s-0034-1365292. Epub 2014 Mar 12. Endoscopy. 2014. PMID: 24623380 No abstract available.

10

A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding.

Lewis A, Freeman-Mills L, de la Calle-Mustienes E, Giráldez-Pérez RM, Davis H, Jaeger E, Becker M, Hubner NC, Nguyen LN, Zeron-Medina J, Bond G, Stunnenberg HG, Carvajal JJ, Gomez-Skarmeta JL, Leedham S, Tomlinson I. Lewis A, et al. Cell Rep. 2014 Aug 21;8(4):983-90. doi: 10.1016/j.celrep.2014.07.020. Epub 2014 Aug 14. Cell Rep. 2014. PMID: 25131200 Free PMC article.

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