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103 results

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Page 1
Homeostasis limits keratinocyte evolution.
Schenck RO, Kim E, Bravo RR, West J, Leedham S, Shibata D, Anderson ARA. Schenck RO, et al. Among authors: leedham s. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2006487119. doi: 10.1073/pnas.2006487119. Epub 2022 Aug 23. Proc Natl Acad Sci U S A. 2022. PMID: 35998218 Free PMC article.
The evolutionary landscape of colorectal tumorigenesis.
Cross W, Kovac M, Mustonen V, Temko D, Davis H, Baker AM, Biswas S, Arnold R, Chegwidden L, Gatenbee C, Anderson AR, Koelzer VH, Martinez P, Jiang X, Domingo E, Woodcock DJ, Feng Y, Kovacova M, Maughan T; S:CORT Consortium; Jansen M, Rodriguez-Justo M, Ashraf S, Guy R, Cunningham C, East JE, Wedge DC, Wang LM, Palles C, Heinimann K, Sottoriva A, Leedham SJ, Graham TA, Tomlinson IPM. Cross W, et al. Among authors: leedham sj. Nat Ecol Evol. 2018 Oct;2(10):1661-1672. doi: 10.1038/s41559-018-0642-z. Epub 2018 Aug 31. Nat Ecol Evol. 2018. PMID: 30177804 Free PMC article.
Fluctuating methylation clocks for cell lineage tracing at high temporal resolution in human tissues.
Gabbutt C, Schenck RO, Weisenberger DJ, Kimberley C, Berner A, Househam J, Lakatos E, Robertson-Tessi M, Martin I, Patel R, Clark SK, Latchford A, Barnes CP, Leedham SJ, Anderson ARA, Graham TA, Shibata D. Gabbutt C, et al. Nat Biotechnol. 2022 May;40(5):720-730. doi: 10.1038/s41587-021-01109-w. Epub 2022 Jan 3. Nat Biotechnol. 2022. PMID: 34980912 Free PMC article.
Immunosuppressive niche engineering at the onset of human colorectal cancer.
Gatenbee CD, Baker AM, Schenck RO, Strobl M, West J, Neves MP, Hasan SY, Lakatos E, Martinez P, Cross WCH, Jansen M, Rodriguez-Justo M, Whelan CJ, Sottoriva A, Leedham S, Robertson-Tessi M, Graham TA, Anderson ARA. Gatenbee CD, et al. Among authors: leedham s. Nat Commun. 2022 Apr 4;13(1):1798. doi: 10.1038/s41467-022-29027-8. Nat Commun. 2022. PMID: 35379804 Free PMC article.
Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia.
Vasquez EG, Nasreddin N, Valbuena GN, Mulholland EJ, Belnoue-Davis HL, Eggington HR, Schenck RO, Wouters VM, Wirapati P, Gilroy K, Lannagan TRM, Flanagan DJ, Najumudeen AK, Omwenga S, McCorry AMB, Easton A, Koelzer VH, East JE, Morton D, Trusolino L, Maughan T, Campbell AD, Loughrey MB, Dunne PD, Tsantoulis P, Huels DJ, Tejpar S, Sansom OJ, Leedham SJ. Vasquez EG, et al. Among authors: leedham sj. Cell Stem Cell. 2022 Aug 4;29(8):1213-1228.e8. doi: 10.1016/j.stem.2022.07.008. Cell Stem Cell. 2022. PMID: 35931031 Free PMC article.
Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission.
Greaves LC, Preston SL, Tadrous PJ, Taylor RW, Barron MJ, Oukrif D, Leedham SJ, Deheragoda M, Sasieni P, Novelli MR, Jankowski JA, Turnbull DM, Wright NA, McDonald SA. Greaves LC, et al. Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):714-9. doi: 10.1073/pnas.0505903103. Epub 2006 Jan 6. Proc Natl Acad Sci U S A. 2006. PMID: 16407113 Free PMC article.
103 results