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Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models.
Cohen AA, van Doremalen N, Greaney AJ, Andersen H, Sharma A, Starr TN, Keeffe JR, Fan C, Schulz JE, Gnanapragasam PNP, Kakutani LM, West AP Jr, Saturday G, Lee YE, Gao H, Jette CA, Lewis MG, Tan TK, Townsend AR, Bloom JD, Munster VJ, Bjorkman PJ. Cohen AA, et al. Among authors: lee ye. Science. 2022 Aug 5;377(6606):eabq0839. doi: 10.1126/science.abq0839. Epub 2022 Aug 5. Science. 2022. PMID: 35857620 Free PMC article.
Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico.
Robbiani DF, Bozzacco L, Keeffe JR, Khouri R, Olsen PC, Gazumyan A, Schaefer-Babajew D, Avila-Rios S, Nogueira L, Patel R, Azzopardi SA, Uhl LFK, Saeed M, Sevilla-Reyes EE, Agudelo M, Yao KH, Golijanin J, Gristick HB, Lee YE, Hurley A, Caskey M, Pai J, Oliveira T, Wunder EA Jr, Sacramento G, Nery N Jr, Orge C, Costa F, Reis MG, Thomas NM, Eisenreich T, Weinberger DM, de Almeida ARP, West AP Jr, Rice CM, Bjorkman PJ, Reyes-Teran G, Ko AI, MacDonald MR, Nussenzweig MC. Robbiani DF, et al. Among authors: lee ye. Cell. 2017 May 4;169(4):597-609.e11. doi: 10.1016/j.cell.2017.04.024. Cell. 2017. PMID: 28475892 Free PMC article.
A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates.
Keeffe JR, Van Rompay KKA, Olsen PC, Wang Q, Gazumyan A, Azzopardi SA, Schaefer-Babajew D, Lee YE, Stuart JB, Singapuri A, Watanabe J, Usachenko J, Ardeshir A, Saeed M, Agudelo M, Eisenreich T, Bournazos S, Oliveira TY, Rice CM, Coffey LL, MacDonald MR, Bjorkman PJ, Nussenzweig MC, Robbiani DF. Keeffe JR, et al. Among authors: lee ye. Cell Rep. 2018 Nov 6;25(6):1385-1394.e7. doi: 10.1016/j.celrep.2018.10.031. Cell Rep. 2018. PMID: 30403995 Free PMC article.
Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
Schoofs T, Barnes CO, Suh-Toma N, Golijanin J, Schommers P, Gruell H, West AP Jr, Bach F, Lee YE, Nogueira L, Georgiev IS, Bailer RT, Czartoski J, Mascola JR, Seaman MS, McElrath MJ, Doria-Rose NA, Klein F, Nussenzweig MC, Bjorkman PJ. Schoofs T, et al. Among authors: lee ye. Immunity. 2019 Jun 18;50(6):1513-1529.e9. doi: 10.1016/j.immuni.2019.04.014. Epub 2019 May 21. Immunity. 2019. PMID: 31126879 Free PMC article.
Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody.
Esswein SR, Gristick HB, Jurado A, Peace A, Keeffe JR, Lee YE, Voll AV, Saeed M, Nussenzweig MC, Rice CM, Robbiani DF, MacDonald MR, Bjorkman PJ. Esswein SR, et al. Among authors: lee ye. Proc Natl Acad Sci U S A. 2020 May 5;117(18):9865-9875. doi: 10.1073/pnas.1919269117. Epub 2020 Apr 22. Proc Natl Acad Sci U S A. 2020. PMID: 32321830 Free PMC article.
Structural classification of neutralizing antibodies against the SARS-CoV-2 spike receptor-binding domain suggests vaccine and therapeutic strategies.
Barnes CO, Jette CA, Abernathy ME, Dam KA, Esswein SR, Gristick HB, Malyutin AG, Sharaf NG, Huey-Tubman KE, Lee YE, Robbiani DF, Nussenzweig MC, West AP Jr, Bjorkman PJ. Barnes CO, et al. Among authors: lee ye. bioRxiv [Preprint]. 2020 Aug 30:2020.08.30.273920. doi: 10.1101/2020.08.30.273920. bioRxiv. 2020. PMID: 32869026 Free PMC article. Updated. Preprint.
SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies.
Barnes CO, Jette CA, Abernathy ME, Dam KA, Esswein SR, Gristick HB, Malyutin AG, Sharaf NG, Huey-Tubman KE, Lee YE, Robbiani DF, Nussenzweig MC, West AP Jr, Bjorkman PJ. Barnes CO, et al. Among authors: lee ye. Nature. 2020 Dec;588(7839):682-687. doi: 10.1038/s41586-020-2852-1. Epub 2020 Oct 12. Nature. 2020. PMID: 33045718 Free PMC article.
Broad and potent neutralizing human antibodies to tick-borne flaviviruses protect mice from disease.
Agudelo M, Palus M, Keeffe JR, Bianchini F, Svoboda P, Salát J, Peace A, Gazumyan A, Cipolla M, Kapoor T, Guidetti F, Yao KH, Elsterová J, Teislerová D, Chrdle A, Hönig V, Oliveira T, West AP, Lee YE, Rice CM, MacDonald MR, Bjorkman PJ, Růžek D, Robbiani DF, Nussenzweig MC. Agudelo M, et al. Among authors: lee ye. J Exp Med. 2021 May 3;218(5):e20210236. doi: 10.1084/jem.20210236. J Exp Med. 2021. PMID: 33831141 Free PMC article.
593 results