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Neoadjuvant chemotherapy plus nivolumab with or without ipilimumab in operable non-small cell lung cancer: the phase 2 platform NEOSTAR trial.
Cascone T, Leung CH, Weissferdt A, Pataer A, Carter BW, Godoy MCB, Feldman H, William WN Jr, Xi Y, Basu S, Sun JJ, Yadav SS, Rojas Alvarez FR, Lee Y, Mishra AK, Chen L, Pradhan M, Guo H, Sinjab A, Zhou N, Negrao MV, Le X, Gay CM, Tsao AS, Byers LA, Altan M, Glisson BS, Fossella FV, Elamin YY, Blumenschein G Jr, Zhang J, Skoulidis F, Wu J, Mehran RJ, Rice DC, Walsh GL, Hofstetter WL, Rajaram R, Antonoff MB, Fujimoto J, Solis LM, Parra ER, Haymaker C, Wistuba II, Swisher SG, Vaporciyan AA, Lin HY, Wang J, Gibbons DL, Jack Lee J, Ajami NJ, Wargo JA, Allison JP, Sharma P, Kadara H, Heymach JV, Sepesi B. Cascone T, et al. Among authors: lee y. Nat Med. 2023 Mar;29(3):593-604. doi: 10.1038/s41591-022-02189-0. Epub 2023 Mar 16. Nat Med. 2023. PMID: 36928818 Free PMC article. Clinical Trial.
Next-Generation Immunotherapies to Improve Anticancer Immunity.
Shi Y, Tomczak K, Li J, Ochieng JK, Lee Y, Haymaker C. Shi Y, et al. Among authors: lee y. Front Pharmacol. 2021 Jan 11;11:566401. doi: 10.3389/fphar.2020.566401. eCollection 2020. Front Pharmacol. 2021. PMID: 33505304 Free PMC article. Review.
Surgical approach does not influence changes in circulating immune cell populations following lung cancer resection.
Deboever N, McGrail DJ, Lee Y, Tran HT, Mitchell KG, Antonoff MB, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Swisher SG, Vaporciyan AA, Walsh GL, Bernatchez C, Vailati Negrao M, Zhang J, Wistuba II, Heymach JV, Cascone T, Gibbons DL, Haymaker CL, Sepesi B. Deboever N, et al. Among authors: lee y. Lung Cancer. 2022 Feb;164:69-75. doi: 10.1016/j.lungcan.2022.01.001. Epub 2022 Jan 8. Lung Cancer. 2022. PMID: 35038676
Shared Nearest Neighbors Approach and Interactive Browser for Network Analysis of a Comprehensive Non-Small-Cell Lung Cancer Data Set.
Schmidt ST, Akhave N, Knightly RE, Reuben A, Vokes N, Zhang J, Li J, Fujimoto J, Byers LA, Sanchez-Espiridion B, Diao L, Wang J, Federico L, Forget MA, McGrail DJ, Weissferdt A, Lin SY, Lee Y, Suzuki E, Kovacs JJ, Behrens C, Wistuba II, Futreal A, Vaporciyan A, Sepesi B, Heymach JV, Bernatchez C, Haymaker C, Cascone T, Zhang J, Bristow CA, Heffernan TP, Negrao MV, Gibbons DL; ICON Team. Schmidt ST, et al. Among authors: lee y. JCO Clin Cancer Inform. 2022 Jul;6:e2200040. doi: 10.1200/CCI.22.00040. JCO Clin Cancer Inform. 2022. PMID: 35944232 Free PMC article.
Phase II study of durvalumab (anti-PD-L1) and trametinib (MEKi) in microsatellite stable (MSS) metastatic colorectal cancer (mCRC).
Johnson B, Haymaker CL, Parra ER, Soto LMS, Wang X, Thomas JV, Dasari A, Morris VK, Raghav K, Vilar E, Kee BK, Eng C, Parseghian CM, Wolff RA, Lee Y, Lorenzini D, Laberiano-Fernandez C, Verma A, Lang W, Wistuba II, Futreal A, Kopetz S, Overman MJ. Johnson B, et al. Among authors: lee y. J Immunother Cancer. 2022 Aug;10(8):e005332. doi: 10.1136/jitc-2022-005332. J Immunother Cancer. 2022. PMID: 36007963 Free PMC article. Clinical Trial.
EMT activates exocytotic Rabs to coordinate invasion and immunosuppression in lung cancer.
Xiao GY, Tan X, Rodriguez BL, Gibbons DL, Wang S, Wu C, Liu X, Yu J, Vasquez ME, Tran HT, Xu J, Russell WK, Haymaker C, Lee Y, Zhang J, Solis L, Wistuba II, Kurie JM. Xiao GY, et al. Among authors: lee y. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2220276120. doi: 10.1073/pnas.2220276120. Epub 2023 Jul 5. Proc Natl Acad Sci U S A. 2023. PMID: 37406091 Free PMC article.
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