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PARIS farnesylation prevents neurodegeneration in models of Parkinson's disease.
Jo A, Lee Y, Kam TI, Kang SU, Neifert S, Karuppagounder SS, Khang R, Kang H, Park H, Chou SC, Oh S, Jiang H, Swing DA, Ham S, Pirooznia S, Umanah GKE, Mao X, Kumar M, Ko HS, Kang HC, Lee BD, Lee YI, Andrabi SA, Park CH, Lee JY, Kim H, Kim H, Kim H, Cho JW, Paek SH, Na CH, Tessarollo L, Dawson VL, Dawson TM, Shin JH. Jo A, et al. Among authors: lee y, lee jy, lee yi, lee bd. Sci Transl Med. 2021 Jul 28;13(604):eaax8891. doi: 10.1126/scitranslmed.aax8891. Sci Transl Med. 2021. PMID: 34321320 Free PMC article.
CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity.
Ko HS, Bailey R, Smith WW, Liu Z, Shin JH, Lee YI, Zhang YJ, Jiang H, Ross CA, Moore DJ, Patterson C, Petrucelli L, Dawson TM, Dawson VL. Ko HS, et al. Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2897-902. doi: 10.1073/pnas.0810123106. Epub 2009 Feb 5. Proc Natl Acad Sci U S A. 2009. PMID: 19196961 Free PMC article.
S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease.
Tsang AH, Lee YI, Ko HS, Savitt JM, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM, Chung KK. Tsang AH, et al. Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4900-5. doi: 10.1073/pnas.0810595106. Epub 2009 Mar 9. Proc Natl Acad Sci U S A. 2009. PMID: 19273858 Free PMC article.
Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage.
Kang HC, Lee YI, Shin JH, Andrabi SA, Chi Z, Gagné JP, Lee Y, Ko HS, Lee BD, Poirier GG, Dawson VL, Dawson TM. Kang HC, et al. Among authors: lee y, lee yi, lee bd. Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14103-8. doi: 10.1073/pnas.1108799108. Epub 2011 Aug 8. Proc Natl Acad Sci U S A. 2011. PMID: 21825151 Free PMC article.
Sulfhydration mediates neuroprotective actions of parkin.
Vandiver MS, Paul BD, Xu R, Karuppagounder S, Rao F, Snowman AM, Ko HS, Lee YI, Dawson VL, Dawson TM, Sen N, Snyder SH. Vandiver MS, et al. Nat Commun. 2013;4:1626. doi: 10.1038/ncomms2623. Nat Commun. 2013. PMID: 23535647 Free PMC article.
Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss.
Lee Y, Karuppagounder SS, Shin JH, Lee YI, Ko HS, Swing D, Jiang H, Kang SU, Lee BD, Kang HC, Kim D, Tessarollo L, Dawson VL, Dawson TM. Lee Y, et al. Among authors: lee yi, lee bd. Nat Neurosci. 2013 Oct;16(10):1392-400. doi: 10.1038/nn.3500. Epub 2013 Aug 25. Nat Neurosci. 2013. PMID: 23974709 Free PMC article.
Protein microarray characterization of the S-nitrosoproteome.
Lee YI, Giovinazzo D, Kang HC, Lee Y, Jeong JS, Doulias PT, Xie Z, Hu J, Ghasemi M, Ischiropoulos H, Qian J, Zhu H, Blackshaw S, Dawson VL, Dawson TM. Lee YI, et al. Among authors: lee y. Mol Cell Proteomics. 2014 Jan;13(1):63-72. doi: 10.1074/mcp.M113.032235. Epub 2013 Oct 8. Mol Cell Proteomics. 2014. PMID: 24105792 Free PMC article.
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