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Syntaxins 6 and 8 facilitate tau into secretory pathways.
Lee WS, Tan DC, Deng Y, van Hummel A, Ippati S, Stevens C, Carmona-Mora P, Ariawan D, Hou L, Stefen H, Tomanic T, Bi M, Tomasetig F, Martin A, Fath T, Palmer S, Ke YD, Ittner LM. Lee WS, et al. Biochem J. 2021 Apr 16;478(7):1471-1484. doi: 10.1042/BCJ20200664. Biochem J. 2021. PMID: 33769438 Free PMC article.
Short-term suppression of A315T mutant human TDP-43 expression improves functional deficits in a novel inducible transgenic mouse model of FTLD-TDP and ALS.
Ke YD, van Hummel A, Stevens CH, Gladbach A, Ippati S, Bi M, Lee WS, Krüger S, van der Hoven J, Volkerling A, Bongers A, Halliday G, Haass NK, Kiernan M, Delerue F, Ittner LM. Ke YD, et al. Among authors: lee ws. Acta Neuropathol. 2015 Nov;130(5):661-78. doi: 10.1007/s00401-015-1486-0. Epub 2015 Oct 5. Acta Neuropathol. 2015. PMID: 26437864
No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapttm1(EGFP)Kit GFP Knockin Mice.
van Hummel A, Bi M, Ippati S, van der Hoven J, Volkerling A, Lee WS, Tan DC, Bongers A, Ittner A, Ke YD, Ittner LM. van Hummel A, et al. Among authors: lee ws. PLoS One. 2016 Oct 13;11(10):e0163236. doi: 10.1371/journal.pone.0163236. eCollection 2016. PLoS One. 2016. PMID: 27736877 Free PMC article.
Tau exacerbates excitotoxic brain damage in an animal model of stroke.
Bi M, Gladbach A, van Eersel J, Ittner A, Przybyla M, van Hummel A, Chua SW, van der Hoven J, Lee WS, Müller J, Parmar J, Jonquieres GV, Stefen H, Guccione E, Fath T, Housley GD, Klugmann M, Ke YD, Ittner LM. Bi M, et al. Among authors: lee ws. Nat Commun. 2017 Sep 7;8(1):473. doi: 10.1038/s41467-017-00618-0. Nat Commun. 2017. PMID: 28883427 Free PMC article.
Selective Spatiotemporal Vulnerability of Central Nervous System Neurons to Pathologic TAR DNA-Binding Protein 43 in Aged Transgenic Mice.
van Hummel A, Chan G, van der Hoven J, Morsch M, Ippati S, Suh L, Bi M, Asih PR, Lee WS, Butler TA, Przybyla M, Halliday GM, Piguet O, Kiernan MC, Chung RS, Ittner LM, Ke YD. van Hummel A, et al. Among authors: lee ws. Am J Pathol. 2018 Jun;188(6):1447-1456. doi: 10.1016/j.ajpath.2018.03.002. Epub 2018 Mar 22. Am J Pathol. 2018. PMID: 29577934 Free article.
Targeting 14-3-3θ-mediated TDP-43 pathology in amyotrophic lateral sclerosis and frontotemporal dementia mice.
Ke YD, van Hummel A, Au C, Chan G, Lee WS, van der Hoven J, Przybyla M, Deng Y, Sabale M, Morey N, Bertz J, Feiten A, Ippati S, Stevens CH, Yang S, Gladbach A, Haass NK, Kril JJ, Blair IP, Delerue F, Ittner LM. Ke YD, et al. Among authors: lee ws. Neuron. 2024 Apr 17;112(8):1249-1264.e8. doi: 10.1016/j.neuron.2024.01.022. Epub 2024 Feb 15. Neuron. 2024. PMID: 38366598
New Insights into IGF-1 Signaling in the Heart.
Lee WS, Abel ED, Kim J. Lee WS, et al. Physiology (Bethesda). 2024 May 7. doi: 10.1152/physiol.00003.2024. Online ahead of print. Physiology (Bethesda). 2024. PMID: 38713091 Review.
Clinical Significance of Residual Ischemia in Acute Myocardial Infarction Complicated by Cardiogenic Shock Undergoing VA-ECMO.
Hong D, Choi KH, Ahn CM, Yu CW, Park IH, Jang WJ, Kim HJ, Bae JW, Kwon SU, Lee HJ, Lee WS, Jeong JO, Park SD, Park TK, Lee JM, Song YB, Hahn JY, Choi SH, Gwon HC, Yang JH. Hong D, et al. Among authors: lee ws. Eur Heart J Acute Cardiovasc Care. 2024 May 3:zuae058. doi: 10.1093/ehjacc/zuae058. Online ahead of print. Eur Heart J Acute Cardiovasc Care. 2024. PMID: 38701179
2,715 results