Lee SM - Search Results

1

Preparation of selective organ-targeting (SORT) lipid nanoparticles (LNPs) using multiple technical methods for tissue-specific mRNA delivery.

Wang X, Liu S, Sun Y, Yu X, Lee SM, Cheng Q, Wei T, Gong J, Robinson J, Zhang D, Lian X, Basak P, Siegwart DJ. Wang X, et al. Among authors: lee sm. Nat Protoc. 2023 Jan;18(1):265-291. doi: 10.1038/s41596-022-00755-x. Epub 2022 Oct 31. Nat Protoc. 2023. PMID: 36316378 Free PMC article. Review.

2

Lipid-Modified Aminoglycosides for mRNA Delivery to the Liver.

Yu X, Liu S, Cheng Q, Wei T, Lee S, Zhang D, Siegwart DJ. Yu X, et al. Adv Healthc Mater. 2020 Apr;9(7):e1901487. doi: 10.1002/adhm.201901487. Epub 2020 Feb 28. Adv Healthc Mater. 2020. PMID: 32108440 Free PMC article.

3

A Systematic Study of Unsaturation in Lipid Nanoparticles Leads to Improved mRNA Transfection In Vivo.

Lee SM, Cheng Q, Yu X, Liu S, Johnson LT, Siegwart DJ. Lee SM, et al. Angew Chem Int Ed Engl. 2021 Mar 8;60(11):5848-5853. doi: 10.1002/anie.202013927. Epub 2021 Feb 1. Angew Chem Int Ed Engl. 2021. PMID: 33305471 Free PMC article.

4

All-In-One Dendrimer-Based Lipid Nanoparticles Enable Precise HDR-Mediated Gene Editing In Vivo.

Farbiak L, Cheng Q, Wei T, Álvarez-Benedicto E, Johnson LT, Lee S, Siegwart DJ. Farbiak L, et al. Adv Mater. 2021 Jul;33(30):e2006619. doi: 10.1002/adma.202006619. Epub 2021 Jun 17. Adv Mater. 2021. PMID: 34137093 Free PMC article.

5

Hydrophobic Optimization of Functional Poly(TPAE-co-suberoyl chloride) for Extrahepatic mRNA Delivery following Intravenous Administration.

Yu X, Liu S, Cheng Q, Lee SM, Wei T, Zhang D, Farbiak L, Johnson LT, Wang X, Siegwart DJ. Yu X, et al. Among authors: lee sm. Pharmaceutics. 2021 Nov 12;13(11):1914. doi: 10.3390/pharmaceutics13111914. Pharmaceutics. 2021. PMID: 34834329 Free PMC article.

6

Zwitterionic Phospholipidation of Cationic Polymers Facilitates Systemic mRNA Delivery to Spleen and Lymph Nodes.

Liu S, Wang X, Yu X, Cheng Q, Johnson LT, Chatterjee S, Zhang D, Lee SM, Sun Y, Lin TC, Liu JL, Siegwart DJ. Liu S, et al. Among authors: lee sm. J Am Chem Soc. 2021 Dec 22;143(50):21321-21330. doi: 10.1021/jacs.1c09822. Epub 2021 Dec 8. J Am Chem Soc. 2021. PMID: 34878786 Free PMC article.

7

Lipid Nanoparticle (LNP) Chemistry Can Endow Unique In Vivo RNA Delivery Fates within the Liver That Alter Therapeutic Outcomes in a Cancer Model.

Johnson LT, Zhang D, Zhou K, Lee SM, Liu S, Dilliard SA, Farbiak L, Chatterjee S, Lin YH, Siegwart DJ. Johnson LT, et al. Among authors: lee sm. Mol Pharm. 2022 Nov 7;19(11):3973-3986. doi: 10.1021/acs.molpharmaceut.2c00442. Epub 2022 Sep 26. Mol Pharm. 2022. PMID: 36154076 Free PMC article.

8

In situ production and secretion of proteins endow therapeutic benefit against psoriasiform dermatitis and melanoma.

Cheng Q, Farbiak L, Vaidya A, Guerrero E, Lee EE, Rose EK, Wang X, Robinson J, Lee SM, Wei T, Miller WE, Alvarez Benedicto E, Lian X, Wang RC, Siegwart DJ. Cheng Q, et al. Among authors: lee sm, lee ee. Proc Natl Acad Sci U S A. 2023 Dec 26;120(52):e2313009120. doi: 10.1073/pnas.2313009120. Epub 2023 Dec 18. Proc Natl Acad Sci U S A. 2023. PMID: 38109533

9

Abnormally High Graphitic Crystallization of Cellulose Nanocrystals.

Lee JE, Jeon WC, Kim YE, Lee GH, Kim J, Kim MJ, Lee SM, Kweon SH, Kwak SK, Chae HG. Lee JE, et al. Among authors: lee sm. ACS Appl Mater Interfaces. 2024 May 11. doi: 10.1021/acsami.4c04015. Online ahead of print. ACS Appl Mater Interfaces. 2024. PMID: 38733565

10

Ultrasensitive and Rapid Circulating Tumor DNA Liquid Biopsy Using Surface-Confined Gene Amplification on Dispersible Magnetic Nano-Electrodes.

Park BC, Soh JO, Choi HJ, Park HS, Lee SM, Fu HE, Kim MS, Ko MJ, Koo TM, Lee JY, Kim YK, Lee JH. Park BC, et al. Among authors: lee sm. ACS Nano. 2024 May 11. doi: 10.1021/acsnano.3c12266. Online ahead of print. ACS Nano. 2024. PMID: 38733343

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