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Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.
Lippert AH, Paluch C, Gaglioni M, Vuong MT, McColl J, Jenkins E, Fellermeyer M, Clarke J, Sharma S, Moreira da Silva S, Akkaya B, Anzilotti C, Morgan SH, Jessup CF, Körbel M, Gileadi U, Leitner J, Knox R, Chirifu M, Huo J, Yu S, Ashman N, Lui Y, Wilkinson I, Attfield KE, Fugger L, Robertson NJ, Lynch CJ, Murray L, Steinberger P, Santos AM, Lee SF, Cornall RJ, Klenerman D, Davis SJ. Lippert AH, et al. Among authors: lee sf. Immunity. 2024 Feb 13;57(2):256-270.e10. doi: 10.1016/j.immuni.2024.01.007. Immunity. 2024. PMID: 38354703 Free article.
Initiation of T cell signaling by CD45 segregation at 'close contacts'.
Chang VT, Fernandes RA, Ganzinger KA, Lee SF, Siebold C, McColl J, Jönsson P, Palayret M, Harlos K, Coles CH, Jones EY, Lui Y, Huang E, Gilbert RJC, Klenerman D, Aricescu AR, Davis SJ. Chang VT, et al. Among authors: lee sf. Nat Immunol. 2016 May;17(5):574-582. doi: 10.1038/ni.3392. Epub 2016 Mar 21. Nat Immunol. 2016. PMID: 26998761 Free PMC article.
Capturing resting T cells: the perils of PLL.
Santos AM, Ponjavic A, Fritzsche M, Fernandes RA, de la Serna JB, Wilcock MJ, Schneider F, Urbančič I, McColl J, Anzilotti C, Ganzinger KA, Aßmann M, Depoil D, Cornall RJ, Dustin ML, Klenerman D, Davis SJ, Eggeling C, Lee SF. Santos AM, et al. Among authors: lee sf. Nat Immunol. 2018 Mar;19(3):203-205. doi: 10.1038/s41590-018-0048-8. Epub 2018 Feb 23. Nat Immunol. 2018. PMID: 29476188 Free PMC article. No abstract available.
Weighing one protein with light.
Lee SF, Klenerman D. Lee SF, et al. Science. 2018 Apr 27;360(6387):378-379. doi: 10.1126/science.aat5851. Science. 2018. PMID: 29700252 No abstract available.
Single-Molecule Light-Sheet Imaging of Suspended T Cells.
Ponjavic A, McColl J, Carr AR, Santos AM, Kulenkampff K, Lippert A, Davis SJ, Klenerman D, Lee SF. Ponjavic A, et al. Among authors: lee sf. Biophys J. 2018 May 8;114(9):2200-2211. doi: 10.1016/j.bpj.2018.02.044. Biophys J. 2018. PMID: 29742413 Free PMC article.
543 results