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Hepatocyte-specific suppression of ANGPTL4 improves obesity-associated diabetes and mitigates atherosclerosis in mice.
Singh AK, Chaube B, Zhang X, Sun J, Citrin KM, Canfrán-Duque A, Aryal B, Rotllan N, Varela L, Lee RG, Horvath TL, Price N, Suárez Y, Fernandez-Hernando C. Singh AK, et al. Among authors: lee rg. J Clin Invest. 2021 Jul 13;131(17):e140989. doi: 10.1172/JCI140989. Online ahead of print. J Clin Invest. 2021. PMID: 34255741 Free PMC article.
MMAB promotes negative feedback control of cholesterol homeostasis.
Goedeke L, Canfrán-Duque A, Rotllan N, Chaube B, Thompson BM, Lee RG, Cline GW, McDonald JG, Shulman GI, Lasunción MA, Suárez Y, Fernández-Hernando C. Goedeke L, et al. Among authors: lee rg. Nat Commun. 2021 Nov 8;12(1):6448. doi: 10.1038/s41467-021-26787-7. Nat Commun. 2021. PMID: 34750386 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 36775562
ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors.
Gordts PL, Nock R, Son NH, Ramms B, Lew I, Gonzales JC, Thacker BE, Basu D, Lee RG, Mullick AE, Graham MJ, Goldberg IJ, Crooke RM, Witztum JL, Esko JD. Gordts PL, et al. Among authors: lee rg. J Clin Invest. 2016 Aug 1;126(8):2855-66. doi: 10.1172/JCI86610. Epub 2016 Jul 11. J Clin Invest. 2016. PMID: 27400128 Free PMC article.
Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease.
Helsley RN, Varadharajan V, Brown AL, Gromovsky AD, Schugar RC, Ramachandiran I, Fung K, Kabbany MN, Banerjee R, Neumann CK, Finney C, Pathak P, Orabi D, Osborn LJ, Massey W, Zhang R, Kadam A, Sansbury BE, Pan C, Sacks J, Lee RG, Crooke RM, Graham MJ, Lemieux ME, Gogonea V, Kirwan JP, Allende DS, Civelek M, Fox PL, Rudel LL, Lusis AJ, Spite M, Brown JM. Helsley RN, et al. Among authors: lee rg. Elife. 2019 Oct 17;8:e49882. doi: 10.7554/eLife.49882. Elife. 2019. PMID: 31621579 Free PMC article.
304 results