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Discovery of novel isoxazolines as anti-tuberculosis agents.
Tangallapally RP, Sun D, Rakesh, Budha N, Lee RE, Lenaerts AJ, Meibohm B, Lee RE. Tangallapally RP, et al. Among authors: lee re. Bioorg Med Chem Lett. 2007 Dec 1;17(23):6638-42. doi: 10.1016/j.bmcl.2007.09.048. Epub 2007 Sep 15. Bioorg Med Chem Lett. 2007. PMID: 17937983 Free PMC article.
Antitubercular nitrofuran isoxazolines with improved pharmacokinetic properties.
Rakesh, Bruhn D, Madhura DB, Maddox M, Lee RB, Trivedi A, Yang L, Scherman MS, Gilliland JC, Gruppo V, McNeil MR, Lenaerts AJ, Meibohm B, Lee RE. Rakesh, et al. Among authors: lee rb, lee re. Bioorg Med Chem. 2012 Oct 15;20(20):6063-72. doi: 10.1016/j.bmc.2012.08.023. Epub 2012 Aug 28. Bioorg Med Chem. 2012. PMID: 22995771 Free PMC article.
Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux.
Lee RE, Hurdle JG, Liu J, Bruhn DF, Matt T, Scherman MS, Vaddady PK, Zheng Z, Qi J, Akbergenov R, Das S, Madhura DB, Rathi C, Trivedi A, Villellas C, Lee RB, Rakesh, Waidyarachchi SL, Sun D, McNeil MR, Ainsa JA, Boshoff HI, Gonzalez-Juarrero M, Meibohm B, Böttger EC, Lenaerts AJ. Lee RE, et al. Among authors: lee rb. Nat Med. 2014 Feb;20(2):152-158. doi: 10.1038/nm.3458. Epub 2014 Jan 26. Nat Med. 2014. PMID: 24464186 Free PMC article.
Pentacyclic nitrofurans that rapidly kill nifurtimox-resistant trypanosomes.
Bruhn DF, Wyllie S, Rodríguez-Cortés A, Carrillo AK, Rakesh, Guy RK, Fairlamb AH, Lee RE. Bruhn DF, et al. Among authors: lee re. J Antimicrob Chemother. 2016 Apr;71(4):956-63. doi: 10.1093/jac/dkv417. Epub 2015 Dec 18. J Antimicrob Chemother. 2016. PMID: 26682963 Free PMC article.
Synthesis and evaluation of pretomanid (PA-824) oxazolidinone hybrids.
Rakesh, Bruhn DF, Scherman MS, Singh AP, Yang L, Liu J, Lenaerts AJ, Lee RE. Rakesh, et al. Among authors: lee re. Bioorg Med Chem Lett. 2016 Jan 15;26(2):388-391. doi: 10.1016/j.bmcl.2015.12.002. Epub 2015 Dec 7. Bioorg Med Chem Lett. 2016. PMID: 26711150 Free PMC article.
888 results