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Page 1
Deubiquitination of proteasome subunits by OTULIN regulates type I IFN production.
Tao P, Wang S, Ozen S, Lee PY, Zhang J, Wang J, Han H, Yang Z, Fang R, Tsai WL, Yang H, Sag E, Topaloglu R, Aksentijevich I, Yu X, Zhou Q. Tao P, et al. Among authors: lee py. Sci Adv. 2021 Nov 19;7(47):eabi6794. doi: 10.1126/sciadv.abi6794. Epub 2021 Nov 19. Sci Adv. 2021. PMID: 34797715 Free PMC article.
Disrupted N-linked glycosylation as a disease mechanism in deficiency of ADA2.
Lee PY, Huang Y, Zhou Q, Schnappauf O, Hershfield MS, Li Y, Ganson NJ, Sampaio Moura N, Delmonte OM, Stone SS, Rivkin MJ, Pai SY, Lyons T, Sundel RP, Hsu VW, Notarangelo LD, Aksentijevich I, Nigrovic PA. Lee PY, et al. J Allergy Clin Immunol. 2018 Oct;142(4):1363-1365.e8. doi: 10.1016/j.jaci.2018.05.038. Epub 2018 Jun 21. J Allergy Clin Immunol. 2018. PMID: 29936104 Free PMC article.
A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1.
Tao P, Sun J, Wu Z, Wang S, Wang J, Li W, Pan H, Bai R, Zhang J, Wang Y, Lee PY, Ying W, Zhou Q, Hou J, Wang W, Sun B, Yang M, Liu D, Fang R, Han H, Yang Z, Huang X, Li H, Deuitch N, Zhang Y, Dissanayake D, Haude K, McWalter K, Roadhouse C, MacKenzie JJ, Laxer RM, Aksentijevich I, Yu X, Wang X, Yuan J, Zhou Q. Tao P, et al. Among authors: lee py. Nature. 2020 Jan;577(7788):109-114. doi: 10.1038/s41586-019-1830-y. Epub 2019 Dec 11. Nature. 2020. PMID: 31827280
Deficiency of Adenosine Deaminase 2 in Adults and Children: Experience From India.
Sharma A, Naidu G, Sharma V, Jha S, Dhooria A, Dhir V, Bhatia P, Sharma V, Bhattad S, Chengappa KG, Gupta V, Misra DP, Chavan PP, Malaviya S, Dudam R, Sharma B, Kumar S, Bhojwani R, Gupta P, Agarwal V, Sharma K, Singhal M, Rathi M, Nada R, Minz RW, Chaturvedi V, Aggarwal A, Handa R, Grossi A, Gattorno M, Huang Z, Wang J, Jois R, Negi VS, Khubchandani R, Jain S, Arostegui JI, Chambers EP, Hershfield MS, Aksentijevich I, Zhou Q, Lee PY. Sharma A, et al. Among authors: lee py. Arthritis Rheumatol. 2021 Feb;73(2):276-285. doi: 10.1002/art.41500. Epub 2020 Dec 26. Arthritis Rheumatol. 2021. PMID: 32892503 Free PMC article.
Comprehensive analysis of ADA2 genetic variants and estimation of carrier frequency driven by a function-based approach.
Jee H, Huang Z, Baxter S, Huang Y, Taylor ML, Henderson LA, Rosenzweig S, Sharma A, Chambers EP, Hershfield MS, Zhou Q, Dedeoglu F, Aksentijevich I, Nigrovic PA, O'Donnell-Luria A, Lee PY. Jee H, et al. Among authors: lee py. J Allergy Clin Immunol. 2022 Jan;149(1):379-387. doi: 10.1016/j.jaci.2021.04.034. Epub 2021 May 15. J Allergy Clin Immunol. 2022. PMID: 34004258 Free PMC article.
TNF inhibition in vasculitis management in adenosine deaminase 2 deficiency (DADA2).
Deuitch NT, Yang D, Lee PY, Yu X, Moura NS, Schnappauf O, Ombrello AK, Stone D, Kuehn HS, Rosenzweig SD, Hoffmann P, Cudrici C, Levy DM, Kessler E, Soep JB, Hay AD, Dalrymple A, Zhang Y, Sun L, Zhang Q, Tang X, Wu Y, Rao K, Li H, Luo H, Zhang Y, Burnham JM, Boehm M, Barron K, Kastner DL, Aksentijevich I, Zhou Q. Deuitch NT, et al. Among authors: lee py. J Allergy Clin Immunol. 2022 May;149(5):1812-1816.e6. doi: 10.1016/j.jaci.2021.10.030. Epub 2021 Nov 12. J Allergy Clin Immunol. 2022. PMID: 34780847
856 results