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Comparison of experimentally measured and computational fluid dynamic predicted deposition and deposition uniformity of monodisperse solid particles in the Vitrocell® AMES 48 air-liquid-interface in-vitro exposure system.
Oldham MJ, Castro N, Zhang J, Lucci F, Kosachevsky P, Rostami AA, Gilman IG, Pithawalla YB, Kuczaj AK, Hoeng J, Lee KM. Oldham MJ, et al. Among authors: lee km. Toxicol In Vitro. 2020 Sep;67:104870. doi: 10.1016/j.tiv.2020.104870. Epub 2020 Apr 21. Toxicol In Vitro. 2020. PMID: 32330563 Free article.
A 6-month inhalation toxicology study in Apoe-/- mice demonstrates substantially lower effects of e-vapor aerosol compared with cigarette smoke in the respiratory tract.
Wong ET, Szostak J, Titz B, Lee T, Wong SK, Lavrynenko O, Merg C, Corciulo M, Simicevic J, Auberson M, Peric D, Dulize R, Bornand D, Loh GJ, Lee KM, Zhang J, Miller JH 4th, Schlage WK, Guedj E, Schneider T, Phillips B, Leroy P, Choukrallah MA, Sierro N, Buettner A, Xiang Y, Kuczaj A, Ivanov NV, Luettich K, Vanscheeuwijck P, Peitsch MC, Hoeng J. Wong ET, et al. Among authors: lee t, lee km. Arch Toxicol. 2021 May;95(5):1805-1829. doi: 10.1007/s00204-021-03020-4. Epub 2021 May 7. Arch Toxicol. 2021. PMID: 33963423 Free PMC article.
A 6-month systems toxicology inhalation study in ApoE-/- mice demonstrates reduced cardiovascular effects of E-vapor aerosols compared with cigarette smoke.
Szostak J, Wong ET, Titz B, Lee T, Wong SK, Low T, Lee KM, Zhang J, Kumar A, Schlage WK, Guedj E, Phillips B, Leroy P, Buettner A, Xiang Y, Martin F, Sewer A, Kuczaj A, Ivanov NV, Luettich K, Vanscheeuwijck P, Peitsch MC, Hoeng J. Szostak J, et al. Among authors: lee t, lee km. Am J Physiol Heart Circ Physiol. 2020 Mar 1;318(3):H604-H631. doi: 10.1152/ajpheart.00613.2019. Epub 2020 Jan 24. Am J Physiol Heart Circ Physiol. 2020. PMID: 31975625 Free article.
E-vapor aerosols do not compromise bone integrity relative to cigarette smoke after 6-month inhalation in an ApoE-/- mouse model.
Reumann MK, Schaefer J, Titz B, Aspera-Werz RH, Wong ET, Szostak J, Häussling V, Ehnert S, Leroy P, Tan WT, Kuczaj A, Audretsch C, Springer F, Badke A, Augat P, Quentanilla-Fend L, Martella M, Lee KM, Peitsch MC, Hoeng J, Nussler AK. Reumann MK, et al. Among authors: lee km. Arch Toxicol. 2020 Jun;94(6):2163-2177. doi: 10.1007/s00204-020-02769-4. Epub 2020 May 14. Arch Toxicol. 2020. PMID: 32409933 Free PMC article.
Biological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols.
Lee KM, Hoeng J, Harbo S, Kogel U, Gardner W, Oldham M, Benson E, Talikka M, Kondylis A, Martin F, Titz B, Ansari S, Trivedi K, Guedj E, Elamin A, Ivanov NV, Vanscheeuwijck P, Peitsch MC, McKinney WJ Jr. Lee KM, et al. Inhal Toxicol. 2018 Nov-Dec;30(13-14):553-567. doi: 10.1080/08958378.2019.1576807. Epub 2019 Mar 8. Inhal Toxicol. 2018. PMID: 30849254
Toxicological Assessment of Flavor Ingredients in E-Vapor Products.
Sciuscio D, Calvino-Martin F, Kumar A, Langston TB, Martin E, Marescotti D, Mathis C, Hoeng J, Peitsch MC, Smith DC, Gogova M, Vanscheeuwijck P, Lee KM. Sciuscio D, et al. Among authors: lee km. Front Toxicol. 2022 Apr 20;4:878976. doi: 10.3389/ftox.2022.878976. eCollection 2022. Front Toxicol. 2022. PMID: 35516526 Free PMC article.
A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment.
Iskandar AR, Zanetti F, Kondylis A, Martin F, Leroy P, Majeed S, Steiner S, Xiang Y, Ortega Torres L, Trivedi K, Guedj E, Merg C, Frentzel S, Ivanov NV, Doshi U, Lee KM, McKinney WJ Jr, Peitsch MC, Hoeng J. Iskandar AR, et al. Among authors: lee km. Intern Emerg Med. 2019 Sep;14(6):863-883. doi: 10.1007/s11739-019-02055-x. Epub 2019 Mar 5. Intern Emerg Med. 2019. PMID: 30835057 Free PMC article.
Assessment of inhalation toxicity of cigarette smoke and aerosols from flavor mixtures: 5-week study in A/J mice.
Wong ET, Luettich K, Cammack L, Chua CS, Sciuscio D, Merg C, Corciulo M, Piault R, Ashutosh K, Smith C, Leroy P, Moine F, Glabasnia A, Diana P, Chia C, Tung CK, Ivanov N, Hoeng J, Peitsch M, Lee KM, Vanscheeuwijck P. Wong ET, et al. Among authors: lee km. J Appl Toxicol. 2022 Oct;42(10):1701-1722. doi: 10.1002/jat.4338. Epub 2022 Jun 8. J Appl Toxicol. 2022. PMID: 35543240 Free PMC article.
2,959 results